Fig. 1
From: Dexamethasone suppresses the proliferation and migration of VSMCs by FAK in high glucose conditions
The roles of FAK and pFAK in signaling pathways. The list of signaling pathways were prepared through searching in KEGG server. Then, the FAK-related genes were enriched to the infection-unrelated metabolic pathways using Cytoscape software (https://cytoscape.org/). The FAK is phosphorylated by SRC, LYN, JAK2, PKA, DCC, PI3K and PCK genes or is auto-phosphorylated after interacting with ITG, VEGF and GPER1 receptors so that only pFAK transduces the cellular proliferation and migration events via cross talking with other signaling pathways or involving other downstream genes