Table 2 Vancomycin initial therapy and trough levels
Variables | 3 to 6 months |  > 6 month–2 years |  > 2 to 6 years |  > 6 to 12 years | |
|---|---|---|---|---|---|
N = 45 | N = 70 | N = 55 | N = 58 | ||
dose (mg/kg/day) | Median (range) | 52.5 (45–60) | 55.6 (50–60) | 57.5 (55–60) | 55.4 (55–60) |
Mean (± SD) | 47.3 ± 13 | 51.1 ± 8.6 | 56.2 ± 6.4 | 54.2 ± 8.2 | |
interval/frequency (hourly) | Median (range) | 6 | 6 | 6 | 6 |
Achieved target vancomycin trough levels | |||||
  Yes- with initial dose | 14 (31.1%) | 31 (44.3%) | 10 (18.2%) | 34 (58.7%) | |
  Mean (± SD) | 10.2 ± 0.6 | 11.3 ± 1.2 | 10.1 ± 0.2 | 12.4 ± 2.1 | |
  No- with initial dose | 31 (68.9%) | 39 (55.7%) | 45 (81.8%) | 24 (41.3%) | |
  Mean (± SD) | 2.9 ± 1.2 | 3.9 ± 1.3 | 2.2 ± 2.0 | 4.2 ± 1.3 | |