Table 3 Post-intervention changes in Vancomycin therapy and trough levels
Variables | 3 to 6 months |  > 6 month–2 years |  > 2 to 6 years |  > 6 to 12 years | |
|---|---|---|---|---|---|
N = 31 | N = 39 | N = 45 | N = 24 | ||
dose (mg/kg/day) | Median (range) | 70 (70–80) | 78 (65–85) | 75 (70–85) | 69 (70–80) |
Mean (± SD) | 71 ± 18 | 75 ± 9.9 | 73 ± 15 | 65 ± 18 | |
interval/frequency (hourly) | Median (range) | 6 | 6 | 6 | 6 |
Achieved target vancomycin trough levels within 10-20Â mg/L | |||||
  Yes- with changed dose | 31 (100.0%) | 39 (100.0%) | 44 (97.8%) | 22 (91.7%) | |
  Mean (± SD) | 11.1 ± 0.9 | 12.3 ± 2.1 | 10.4 ± 0.2 | 12.8 ± 1.3 | |
  No- with changed dose | 0.00 (0.0%) | 0.00 (0.0%) | 1 (2.2%) | 02 (8.3%) a | |
  Mean (± SD) | - | - | 4.2 ± 2.0 | 25.6 ± 3.3 | |