| Treatment Group | P-value | ||||
---|---|---|---|---|---|---|
granisetron + sertraline (n = 27) | placebo + sertraline (n = 21) | |||||
Mean ± SD | Count (%) | Mean ± SD | Count (%) | |||
Age (years) | 35.48 ± 10.97 |  | 33.44 ± 9.35 |  | 0.49 | |
Duration of disease (years) | 2.33 ± 3.48 |  | 3.44 ± 5.05 |  | 0.37 | |
Gender | Female | Â | 20 (74.1%) | Â | 13 (61.9%) | 0.53 |
Male | Â | 7 (25.9%) | Â | 8 (38.1%) | ||
Education | Illiterate | Â | 1 (3.7%) | Â | 0 (0.0%) | 0.21 |
Primary | Â | 0 (0.0%) | Â | 1 (4.8%) | ||
Secondary | Â | 2 (7.4%) | Â | 1 (4.8%) | ||
High school diploma | Â | 1 (3.7%) | Â | 5 (23.8%) | ||
University Education | Â | 23 (85.2% | Â | 14 (66.7%) | ||
Marital status | Single | Â | 16 (59.3%) | Â | 13 (61.9%) | 1 |
Married | Â | 11 (40.7%) | Â | 8 (38.1%) | ||
Employment | Employed | Â | 15 (55.6%) | Â | 10 (47.6%) | 0.46 |
Unemployed | Â | 7 (25.9%) | Â | 3 (14.3%) | ||
Housewife | Â | 5 (18.5%) | Â | 5 (23.8%) | ||
Student | Â | 0 (0.0%) | Â | 3 (14.3%) | ||
Previous treatment | Yes | Â | 12 (44.4%) | Â | 12 (57.1%) | 0.56 |
No | Â | 15 (55.6%) | Â | 9 (42.9%) | ||
Y-BOCS score (week 0) | Total | 28.92 ± 7.15 |  | 27.5 ± 4.95 |  | 0.44 |
Obsession | 16.62 ± 3.04 |  | 14.75 ± 3.79 |  | 0.06 | |
Compulsion | 12.48 ± 5.41 |  | 12.5 ± 3.2 |  | 0.98 |