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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: β-Hydroxyphosphocarnitine modifies fibrosis, steatosis and improves liver function in non-alcoholic steatohepatitis induced in rats

Fig. 2

Effect of β-HPC on SREBP-1 expression in rats with NASH. The expression of SREBP-1 was determined by immunohistochemistry. Positive reactions can be seen in brown. A and B Livers from control and β-HPC groups respectively: staining reveals scattered isolated positive cells throughout the parenchyma. C Non-treated NASH group: SREBP-1 localization in liver with steatosis and fibrosis: many immunopositive cells were observed throughout the parenchyma. Black arrow indicates positive cytoplasm stain. Red arrow indicates positive nuclei stain. D NASH group treated with 100 mg/Kg β-HPC: showing a reduced amount of immunopositive cells: there were occasional and faint immune positive hepatocytes through the parenchyma. Magnification of 40X

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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