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Fig. 9 | BMC Pharmacology and Toxicology

Fig. 9

From: Accidental lead in contaminated pipe-borne water and dietary furan intake perturbs rats’ hepatorenal function altering oxidative, inflammatory, and apoptotic balance

Fig. 9

Effect of accidental co-exposure of experimental rats’ models to Lead and Furan in diet and water respectively on the hepatic and renal levels of 8-OHdG, Casp-9 and Casp-3 in rats. Furan, 8 mg/kg; Lead, 100 μg/; Furan + PbAc1, (8 mg/kg + 1.0 μg/L) mg/kg; Furan + PbAc2, (8 mg/kg + 10 μg/L) mg/kg; Furan + PbAc3, (8 mg/kg + 100 μg/L) mg/kg. Values are expressed as mean ± SD for five rats per treatment cohort. The connecting lines indicate groups compared to one another, and the significance level was set at (p < 0.05); p < 0.05: indicates the level of significance; p > 0.05: Not significant. 8-OHdG: 8-hydroxydeoxyguanosine, Casp: Caspase

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