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Fig. 7 | BMC Pharmacology and Toxicology

Fig. 7

From: Human targeted phenobarbital presents a poor substrate of gut microbiome deciphering new drug targets beyond pharmacokinetic curbs

Fig. 7

Two-dimensional interaction diagrams of phenobarbital docked in the active sites of (A) transport protein Escherichia coli BL21(DE3) (PDB ID: 5A9D) and (B) membrane protein Escherichia coli K-12, Lama glama (PDB ID: 6GS4). Three-dimensional interaction diagrams of phenobarbital docked in the active sites of (C) transport protein Escherichia coli BL21(DE3) (PDB ID: 5A9D) and (D) membrane protein Escherichia coli K-12, Lama glama (PDB ID: 6GS4). Surface binding pose of phenobarbital in the active site of protein (E) PDB ID: 5A9D and (F) PDB ID: 6GS4; with conformational behavior within the surface-active site of target proteins

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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