Table 2 Skin irritation study using Draize scoring of formalin treated and gel treated rats as compared with untreated rats
| Â | Time (hrs) | Untreated rat (Control) | Formalin Treated rats | ALP-loaded NLCs Treated rats |
|---|---|---|---|---|
Erythema | 1 | 0 | 3 | 1 |
12 | 0 | 3 | 0 | |
24 | 0 | 2 | 0 | |
Edema | 1 | 0 | 1 | 0 |
12 | 0 | 2 | 0 | |
24 | 0 | 2 | 0 | |
PDI | 1 | 0 | 4 | 1 |
12 | 0 | 5 | 0 | |
24 | 0 | 4 | 0 | |
PDII | Â | 0 | 4.33 (Moderate) | 0.33 (Non-significant) |