Fig. 1

Using ESPript3, the amino acid sequences of ACE2 of 6M0J were aligned with the secondary structure of ACE2, demonstrating the amino acids’ solvent accessibility.. Two regions of ACE2, α1 helical protease domain (PD) and β4 - β5 sheets (red rectangles surrounding the 49 amino acids), contained the majority of the amino acids that interacted with RBD (red triangles)