Table 2 Characteristics of the studies included in the systematic review about AUC (children)
Study | Design of study | Country of study | Duration of therapy (days) | Age of children | No. of children | AUC (mg・h/L) of children | |
|---|---|---|---|---|---|---|---|
Thrombocytopenia | Non-thrombocytopenia | ||||||
Kosaka 2009 [43] | Prospective study | Japan | Mean: 47.5 ± 48.4 | Mean: 1.2 ± 0.8 | 4 (0/4) | ― | AUC24 207.6, 361.2a |
Matsumoto 2014 [44] | Prospective observational study | Japan | Mean: 17.8 ± 7.0 | Mean: 6.4 ± 3.2 | 5 (1/4) | AUC24 180.5b | AUC24 116.5, 161.1, 186.4, 231.2 |