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Table 6 GRADE assessment of meta-analysis

From: Safety of linezolid in patients with decreased renal function and trough monitoring: a systematic review and meta-analysis

Factor

Consequence

Study design

⊕⊕⊖⊖

Risk of bias

↓a

Inconsistency of results

→

Indirectness of evidence

→

Imprecision

→

Publication bias

→

Large magnitude of effect

↑b

All plausible confounding would reduce the demonstrated effect or increase the effect if no effect was observed

→

Dose-response gradient

→

GRADE quality

⊕⊕⊖⊖

  1. GRADE assessment criteria; ⊕⊕⊕⊕:high, ⊕⊕⊕⊖:moderate, ⊕⊕⊖⊖:low, ⊕⊖⊖⊖:very low
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