Fig. 3
From: GAS-STING signaling plays an essential pathogenetic role in Doxorubicin-Induced Cardiotoxicity
Knockdown of STING improved survival and cardiac function of DOX-treated mice (A-E). A Effect of STING knockdown on the 14-day survival rate after DOX injection (n = 10). B Effect of STING knockdown on HW/TW. C Representative echocardiographic images of each group (n = 4). D Effect of STING knockdown on left ventricle ejection fraction, left ventricle fractional shortening, left ventricular end-diastolic dimension and left ventricular end-systolic dimension of each group (n = 4). E Effect of STING knockdown on DOX-induced LDH, cTNT and CK-MB release (n = 4)