Fig. 5From: Celecoxib activates autophagy by inhibiting the mTOR signaling pathway and prevents apoptosis in nucleus pulposus cellsCXB inhibited mTOR signaling pathway and downstream molecules. A-E NPCs were treated with IL-1β alone or with 10 µM CXB. 200 nM RAPA was added in addition to IL-1β and CXB as a positive control. Phosphorylation of mTOR, Akt, rpS6, and 4E-BP1 were analyzed for activity relating to autophagy, cell growth, and mRNA translation. The grouping of blots were cropped from different parts of different blots. Data were represented as mean with SD. *P ≤ 0.05, **P ≤ 0.01, *** P ≤ 0.001Back to article page