Skip to main content

Table 2 General characteristics of the included studies

From: Association between anticholinergic activity and xerostomia and/ or xerophthalmia in the elderly: systematic review

 

Study Year

Study design

Population

Country

Sex (female %)

Age (y)

N

Duration (Ma)

Anticholinergicdrug use and peripheral effects

Thomson WM. 1993

Cross-sectional study

Nursing home residents and geriatric hospital residents

New Zealand

60%

82.5 ± 2.4𝜹

359

Katz IR. 1988

Cross-sectional study

Congregate Housing population

United States

33%

83.2 ± 5.8𝜹

53

Ness J. 2006

Prospective cohort study

Community-dwelling patients

United States

2.1%

74.3

532

3

Desoutter A. 2012

Cross-sectional study

Long term geriatric ward

France

no data

84.6 ± 8.4𝜹

769

Anticholinergic burden and peripheral effects

Rudolph JL. 2008

Retrospective Cohort study

Community-dwelling patients

United States

3%

78.7 ± 5.3𝜹

132

9

Prospective Cohort study

0%

71.5 ± 11.6𝜹

117

10

Kersten H. 2012

Cross-sectional study

Nursing home residents

Norway

79.3%

> 73

87

Kersten H. 2013

Randomized Controlled Trial

Nursing home residents

Norway

79.3%

> 73

87

2

Tiisanoja A. 2017

Cross-sectional study

Community-dwelling patients

Finland

73.6%

79.6 ± 3.7𝜹

152

Inkeri NM. 2019

Cross-sectional study

Community-dwelling patients

Finland

50.9%

> 65

1.084

Lavrador M. 2021

Case control Study

Patients admitted in Internal Medicine wards

Portugal

50

81.7 ± 7.8 𝜹

250

12

  1. 𝜹 Average (Standard deviation); a M: months