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Table 4 Oxidizing effects of tartrazine at different concentrations using mutant Saccharomyces cerevisiae strains

From: Cytotoxic and mutagenic effects of the food additive tartrazine on eukaryotic cells

Test strains

Treatments

NC

PC

TRZ

Saline

H 2 O 2

400 µg/mL

200 µg/mL

100 µg/mL

SODWT

0.75 ± 0.50

14.35 ± 0.25ª

0.00 ± 0.00

0.30 ± 0.50

0.00 ± 0.00

Sod1

1.50 ± 0.57

14.73 ± 2.28a

1.00 ± 0.80

0.80 ± 0.80

0.00 ± 0.00

Sod2∆

1.25 ± 0.50

13.82 ± 0.45a

0.50 ± 0.57

0.75 ± 0.89

0.00 ± 0.00

Sod1Sod2∆

2.00 ± 0.81

11.35 ± 1.01a

0.00 ± 0.00

0.00 ± 0.00

0.00 ± 0.00

Cat∆

1.25 ± 0.50

15.10 ± 0.70a

1.00 ± 0.80

0.75 ± 0.50

0.00 ± 0.00

Sod1Cat

1.50 ± 0.57

12.37± 0.22a

0.10± 1.15

0.75± 0.90

0.00 ± 0.00

  1. Values ​​are mean ± SD of inhibition halos measured in Petri dishes (0-40 mm). ANOVA one-way followed by the Tukey post-test; a p<0.001 compared to the NC (saline),b p<0.001 compared to the PC (H2O2); TRZ Tartrazine