Study on the thermal stability of nab-paclitaxel during hyperthermic intraperitoneal chemotherapy

Table 6 The peak area, C_P, C_P1 and paclitaxel binding rate of three batches of albumin-bound paclitaxel at different temperatures

Batch number	Temperature (°C)	Peak area	C_P	C_P1	Paclitaxel binding rate (%)	Mean value (%)
B042001249	25	6.0256	101.55	0.016708544	96.70	96.7
	25	6.0806	101.55	0.016861054	96.67	96.7
	37	5.9337	101.55	0.016453712	96.75	96.8
	37	5.9248	101.55	0.016429033	96.76	96.8
	41	5.685	101.55	0.015764085	96.89	96.9
	41	5.6808	101.55	0.015752439	96.89	96.9
	42	5.7725	101.55	0.016006716	96.84	96.8
	42	5.7651	101.55	0.015986196	96.85	96.8
	43	6.5324	101.55	0.018113862	96.43	96.4
	43	6.54	101.55	0.018134937	96.42	96.4
B042001250	25	7.5575	101.36	0.020956389	95.86	95.9
	25	7.5572	101.36	0.020955557	95.86	95.9
	37	7.3853	101.36	0.020478891	95.95	96.0
	37	7.371	101.36	0.020439238	95.96	96.0
	41	7.3002	101.36	0.020242915	96.00	96.0
	41	7.2888	101.36	0.020211304	96.01	96.0
	42	6.3328	101.36	0.017560386	96.53	96.5
	42	6.3331	101.36	0.017561218	96.53	96.5
	43	8.2648	101.36	0.02291768	95.47	95.5
	43	8.2573	101.36	0.022896883	95.48	95.5
B042001251	25	7.2225	101.54	0.020027459	96.05	96.1
	25	7.2217	101.54	0.02002524	96.05	96.1
	37	6.9538	101.54	0.019282374	96.20	96.2
	37	6.9525	101.54	0.019278769	96.20	96.2
	41	6.5789	101.54	0.018242804	96.40	96.4
	41	6.5866	101.54	0.018264155	96.40	96.4
	42	6.2865	101.54	0.017432	96.56	96.6
	42	6.2864	101.54	0.017431723	96.56	96.6
	43	7.5801	101.54	0.021019057	95.85	95.9
	43	7.5687	101.54	0.020987446	95.86	95.9

ISSN: 2050-6511