Fig. 4

The expression of miR-34a and DRP1 in HEI-OC1 cells treated with 20 µM cisplatin for 24 h. A RT‒PCR showed that the expression of miR-34a was increased in the cisplatin group. B-D The levels of DRP1 and LC3II/I were detected using Western blotting in HEI-OC1 cells. B Representative Western blot analysis of DRP1 and LC3-II/I. C, D Relative expression of DRP1 and LC3-II/I. Data are presented as the mean ± SEM of three independent experiments. *p < 0.05, **p < 0.01