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Fig. 5 | BMC Pharmacology and Toxicology

Fig. 5

From: Thiram, an inhibitor of 11ß-hydroxysteroid dehydrogenase type 2, enhances the inhibitory effects of hydrocortisone in the treatment of osteosarcoma through Wnt/β-catenin pathway

Fig. 5

Effects of HC and thiram on proteins of Wnt/β-catenin pathway in osteosarcoma cells. A HC and thiram affect the proteins in Wnt/β-catenin pathway in Saos-2 cells. B HC and thiram affect the proteins in Wnt/β-catenin pathway in Mg63 cells. C HC and thiram affect the proteins in Wnt/β-catenin pathway of K7M2-WT cells. D Combined treatment with HC and thiram significantly reduced the MMP-7 concentration (left: MG63, middle: Saos-2, right: K7M2-wt). The histograms show the quantitative analysis of the samples. Measurement data were measured using the mean ± SD. The statistical significance of differences between two groups was analyzed using the unpaired t test. Repetition = 3 *p < 0.05, **p < 0.01, and ***p < 0.001

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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