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Table 3 Summary of the literature review on the toxicity profile of pembrolizumab

From: Analysis of the relation between adverse events and overall survival in patients treated with pembrolizumab as a first-line treatment for metastatic NSCLC

 

Keynote-042 [9] %

Keynote-024 [8] %

Real-world study %

Cutaneous Toxicities

14.0

22.1

30.1 (p = 0.0008)

Endocrinological Toxicities

17.0

17.5

20.4 (p = 0.0005)

Gastrointestinal Toxicities

13

32

27.5 (p = 0.5)

Overall Toxicities

63

76.6

77.5 (p = 0.006)