Variables | Censored | Events | Simple. HR | (95% CI) | p-valuea | Adj. HR | (95% CI) | p-valueb | |||
---|---|---|---|---|---|---|---|---|---|---|---|
n | (%) | n | (%) | ||||||||
Age category | Â | Â | Â | Â | Â | Â | 0.907 | Â | Â | 0.240 | |
 | ≤ 61 years | 95 | 87.9 | 13 | 12.1 | 1.00 | (ref.) |  | 1.00 | (ref.) |  |
 | ≥ 62 years | 90 | 88.2 | 12 | 11.8 | 1.05 | (0.47, 2.32) |  | 0.44 | (0.11, 1.72) |  |
Gender | Â | Â | Â | Â | Â | Â | Â | 0.896 | Â | Â | 0.069 |
 | Male | 92 | 86.0 | 15 | 14.0 | 1.00 | (ref.) |  | 1.00 | (ref.) |  |
 | Female | 68 | 82.9 | 13 | 17.1 | 0.95 | (0.41, 2.20) |  | 0.26 | (0.06, 1.11) |  |
Ethnicity | Â | Â | Â | Â | Â | Â | Â | 0.765 | Â | Â | 0.257 |
 | Malay | 87 | 90.6 | 9 | 9.4 | 1.00 | (ref.) |  | 1.00 | (ref.) |  |
 | Chinese | 64 | 86.5 | 10 | 13.5 | 1.67 | (0.64, 4.37) |  | 0.65 | (0.19, 2.23) |  |
 | Indian | 25 | 89.3 | 3 | 10.7 | 1.17 | (0.30, 4.52) |  | 0.86 | (0.13, 5.63) |  |
 | Others | 9 | 75.0 | 3 | 25.0 | 1.27 | (0.31, 5.13) |  | 0.08 | (0.01, 0.95) |  |
Smoking status | Â | Â | Â | Â | Â | Â | 0.147 | Â | Â | 0.124 | |
 | No | 137 | 85.6 | 23 | 14.4 | 1.00 | (ref.) |  | 1.00 | (ref.) |  |
 | Yes | 48 | 96.0 | 2 | 4.0 | 0.34 | (0.08, 1.46) |  | 0.19 | (0.02, 1.57) |  |
Stroke category |  |  |  |  |  |  | < 0.001* |  |  | 0.004* | |
 | Ischemic stroke | 171 | 92.4 | 14 | 7.6 | 1.00 | (ref.) |  | 1.00 | (ref.) |  |
 | Hemorrhagic stroke | 14 | 56.0 | 11 | 44.0 | 6.60 | (2.86, 15.21) |  | 10.61 | (2.1, 53.68) |  |
Stroke episode | Â | Â | Â | Â | Â | Â | 0.029* | Â | Â | 0.245 | |
 | First | 137 | 93.8 | 9 | 6.2 | 1.00 | (ref.) |  | 1.00 | (ref.) |  |
 | Recurrent | 48 | 75.0 | 16 | 25.0 | 2.54 | (1.10,5.89) |  | 1.99 | (0.62, 6.32) |  |
Number of comorbidities | Â | Â | Â | Â | Â | Â | 0.148 | Â | Â | 0.020* | |
 | ≤ 2comorbidities | 107 | 91.5 | 10 | 8.5 | 1.00 | (ref.) |  | 1.00 | (ref.) |  |
 | ≥ 3comorbidities | 78 | 83.9 | 15 | 16.1 | 1.18 | (0.81, 4.09) |  | 6.60 | (1.34, 32.44) |  |
Number of medications | Â | Â | Â | Â | Â | Â | 0.129 | Â | Â | 0.054 | |
 | ≤ 10medications | 103 | 91.2 | 10 | 8.8 | 1.00 | (ref.) |  | 1.00 | (ref.) |  |
 | ≥ 11medications | 82 | 84.5 | 15 | 15.5 | 0.49 | (0.19, 1.23) |  | 0.19 | (0.04, 1.03) |  |
Anti-platelets | Â | Â | Â | Â | Â | Â | 0.019* | Â | Â | 0.068 | |
 | No | 29 | 63.0 | 17 | 37.0 | 1.00 | (ref.) |  | 1.00 | (ref.) |  |
 | Yes | 156 | 95.1 | 8 | 4.9 | 0.32 | (0.12,0.83) |  | 4.87 | (0.89, 26.58) |  |
Statins |  |  |  |  |  |  |  | < 0.001* |  |  | 0.050* |
 | No | 33 | 64.7 | 18 | 35.3 | 1.00 | (ref.) |  | 1.00 | (ref.) |  |
 | Yes | 152 | 95.6 | 7 | 4.4 | 0.18 | (0.07,0.44) |  | 0.25 | (0.06, 1.00) |  |
Proton pump inhibitors | Â | Â | Â | Â | Â | Â | 0.866 | Â | Â | 0.440 | |
 | No | 49 | 90.7 | 5 | 9.3 | 1.00 | (ref.) |  | 1.00 | (ref.) |  |
 | Yes | 136 | 87.2 | 20 | 12.8 | 0.92 | (0.33,2.54) |  | 0.50 | (0.09, 2.90) |  |
Anti-diabetic | Â | Â | Â | Â | Â | Â | 0.278 | Â | Â | 0.006* | |
 | No | 112 | 86.2 | 18 | 13.8 | 1.00 | (ref.) |  | 1.00 | (ref.) |  |
 | Yes | 73 | 91.3 | 7 | 8.8 | 0.62 | (0.26,1.48) |  | 0.13 | (0.03, 0.55) |  |
Anti-hypertensive | Â | Â | Â | Â | Â | Â | 0.060 | Â | Â | 0.379 | |
 | No | 127 | 86.4 | 20 | 13.6 | 1.00 | (ref.) |  | 1.00 | (ref.) |  |
 | Yes | 58 | 92.1 | 5 | 7.9 | 0.35 | (0.12,1.04) |  | 0.52 | (0.12, 2.22) |  |
Anti-infective | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.019* | |
 | No | 150 | 96.8 | 5 | 3.2 | 1.00 | (ref.) | 0.009* | 1.00 | (ref.) |  |
 | Yes | 35 | 63.6 | 20 | 36.4 | 4.38 | (1.45,13.25) |  | 13.10 | (1.54, 111.41) |  |