This section considers submissions that focus on receptor pharmacology, signal transduction, pharmacokinetics and pharmacogenomics relating to all organ systems.
Bupivacaine inhibits a small conductance calcium‐activated potassium type 2 channel in human embryonic kidney 293 cells
Bupivacaine blocks many ion channels in the heart muscle, causing severe cardiotoxicity. Small-conductance calcium-activated potassium type 2 channels (SK2 channels) are widely distributed in the heart cells a...
Citation: BMC Pharmacology and Toxicology 2021 22:15