This section considers submissions that focus on computational simulation including the analysis of structure-activity relationships, molecular modeling and data mining.
Prediction of lisinopril pediatric dose from the reference adult dose by employing a physiologically based pharmacokinetic model
This study aimed to assess the pediatric lisinopril doses using an adult physiological based pharmacokinetic (PBPK) model. As the empirical rules of dose calculation cannot calculate gender-specific pediatric ...
Citation: BMC Pharmacology and Toxicology 2020 21:56