Volume 13 Supplement 1

18th Scientific Symposium of the Austrian Pharmacological Society (APHAR)

Meeting abstracts

Edited by Peter Holzer and Thomas Griesbacher

18th Scientific Symposium of the Austrian Pharmacological Society (APHAR). Joint meeting with the Croatian, Serbian and Slovenian Pharmacological Societies. Go to conference site.

Graz, Austria20-21 September 2012

Concatenated PDF 13S1

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Statins reduce endogenous dolichol levels in the neuroblastoma cell line SH-SY5Y

Authors: Bihter Atil, Evelyn Sieczkowski and Martin Hohenegger

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A51

Content type: Meeting abstract Published on: 17 September 2012
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LRET-based distance measurements in the mammalian glutamate transporter EAAT3

Authors: Kusumika Saha, SanthoshKannan Venkatesan, Azmat Sohail, Thomas Stockner, Simon Bulling, Gerhard F Ecker, Harald H Sitte and Walter Sandtner

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A52

Content type: Meeting abstract Published on: 17 September 2012
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Decrypting structural and functional changes in LeuT_Aaat atomic level employing LRET

Authors: Azmat Sohail, Simon Bulling, Peggy Stolt-Bergner, Oliver Kudlacek, Gerhard F Ecker, Michael Freissmuth, Thomas Stockner, Harald H Sitte and Walter Sandtner

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A53

Content type: Meeting abstract Published on: 17 September 2012
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The N-terminus acts as a lever to support amphetamine-induced substrate efflux by the serotonin transporter

Authors: Sonja Sucic, Carina Kern, Harald H Sitte and Michael Freissmuth

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A54

Content type: Meeting abstract Published on: 17 September 2012
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How does the carboxyl terminus assist folding and ER export of the serotonin transporter?

Authors: Ali El-Kasaby, Florian Koban, Michael Freissmuth and Sonja Sucic

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A55

Content type: Meeting abstract Published on: 17 September 2012
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Calmodulin kinase II regulates amphetamine-induced reverse transport in dopamine and serotonin transporters

Authors: Thomas Steinkellner, Therese Montgomery, Jae-Won Yang, Matthias Rickhag, Sonja Sucic, Ype Elgersma, Oliver Kudlacek, Michael Freissmuth, Ulrik Gether and Harald H Sitte

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A56

Content type: Meeting abstract Published on: 17 September 2012
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Deciphering structural rearrangements during transport process in the bacterial transporter GltPh, homolog to mammalian glutamate transporter

Authors: SanthoshKannan Venkatesan, Azmat Sohail, Walter Sandtner, Thomas Stockner, Gerhard F Ecker and Harald H Sitte

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A57

Content type: Meeting abstract Published on: 17 September 2012
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Peptide YY and neuropeptide Y in regulation of pain and spatial learning and memory

Authors: Piyush Jain, Ahmed Hassan, Herbert Herzog and Peter Holzer

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A58

Content type: Meeting abstract Published on: 17 September 2012
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Identifying forces that stabilize the oligomeric state of bacterial homologs of neurotransmitter transporters

Authors: Kumaresan Jayaraman, Azmat Sohail, Michael Freissmuth, Harald H Sitte and Thomas Stockner

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A59

Content type: Meeting abstract Published on: 17 September 2012
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A conformational change of the domain IV S6 segment of the voltage-gated sodium channel during inactivation

Authors: Vaibhavkumar S Gawali, René Cervenka, Péter Lukács, Xaver Koenig, Lena Rubi, Ágnes K Mike, Karlheinz Hiber and Hannes Todt

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A60

Content type: Meeting abstract Published on: 17 September 2012
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Functional and physical interactions between P2Y receptors and ion channels

Authors: Hend Gafar, Giri K Chandaka and Stefan Boehm

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A61

Content type: Meeting abstract Published on: 17 September 2012
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Does pulmonary surfactant generally affect antimicrobial activity?

Authors: Richard Schwameis, Sabine Strommer, Markus Zeitlinger and Robert Sauermann

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A62

Content type: Meeting abstract Published on: 17 September 2012
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Pharmacochaperoning of the ER-retained A₁adenosine receptor

Authors: Justyna Kusek, Christian W Gruber, Christian Nanoff and Michael Freissmuth

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A63

Content type: Meeting abstract Published on: 17 September 2012
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Statins impact on epigenetics of tumor cells

Authors: Murtaza Kulaksiz and Martin Hohenegger

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A64

Content type: Meeting abstract Published on: 17 September 2012
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Therapeutic potential of a novel multifunctional iron chelator on cognitive decicits and insulin degrading enzyme expression in a rat model of sporadic Alzheimer's disease

Authors: Ana Knezović, Marina Knapić, Jelena Osmanović-Barilar, Silvia Mandel, Moussa Youdim, Peter Riederer and Melita Šalković-Petrišić

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A65

Content type: Meeting abstract Published on: 17 September 2012
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IL-6-mediated migration of human metastatic melanoma cells is reduced by simvastatin treatment

Authors: Christine Wasinger, Christoph Minichsdorfer and Martin Hohenegger

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A66

Content type: Meeting abstract Published on: 17 September 2012
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Pharmacological stimulation of murine and human hematopoetic stem cells

Authors: Christian Bergmayr, Christian Balasz, Zarzar Kazemi, Filza Hussain, Thomas Bauer, Herbert Strobl, Peter Selzer, Wolfgang Strohmaier, Michael Freissmuth and Eva Zebedin-Brandl

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A67

Content type: Meeting abstract Published on: 17 September 2012
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Which conformation does the ABC transporter P-glycoprotein adopt in the physiological membrane environment?

Authors: Thomas Stockner, Yaprak Dönmez, Zahida Parveen and Peter Chiba

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A68

Content type: Meeting abstract Published on: 17 September 2012
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Biophysical characterization of Ca_V1.4 L-type calcium channel mutants causing congenital stationary night blindness type 2 in humans

Authors: Klaus W Schicker, Verena Burtscher, Dagmar Knoflach, Anamika Singh, Thomas Stockner and Alexandra Koschak

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A69

Content type: Meeting abstract Published on: 17 September 2012
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New structural determinants of charged local anaesthetic block of voltage-gated sodium channels

Authors: Péter Lukács, René Cervenka, Vaibhavkumar S Gawali, Xaver Koenig, Ágnes K Mike, Lena Rubi, Karlheinz Hilber and Hannes Todt

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A70

Content type: Meeting abstract Published on: 17 September 2012
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Bacterial peptidoglycan primes the immune system leading to increased sickness in response to lipopolysaccharide

Authors: Aitak Farzi, Evelin Painsipp and Peter Holzer

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A71

Content type: Meeting abstract Published on: 17 September 2012
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Soluble osteopontin concentrations in serum and ascites of women with advanced serous ovarian cancer

Authors: Katarina Černe, Ana Bačnik, Katarina Galič-Jerman and Borut Kobal

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A72

Content type: Meeting abstract Published on: 17 September 2012
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Expression of organic cation transporter 3 (SLC22A3) and plasma membrane monoamine transporter (SLC29A4) in human umbilical vein endothelial cells and their relevance for histamine uptake

Authors: Polonca Ferk, Metoda Lipnik-Štangelj, Mojca Kržan and Katarina Černe

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A73

Content type: Meeting abstract Published on: 17 September 2012
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Characterization of colistin tissue pharmacokinetics by microdialysis

Authors: Peter Matzneller, William Couet, Patrice Gobin, Markus Müller and Markus Zeitlinger

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A74

Content type: Meeting abstract Published on: 17 September 2012
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The galanin system in depression and antidepressant treatment: focus on the locus coeruleus

Authors: Simone B Sartori, Anupam Sah, Baosheng Zhao, Inga Neumann, Rainer Landgraf and Nicolas Singewald

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A75

Content type: Meeting abstract Published on: 17 September 2012
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ABC transporters of the liver fluke Fasciola hepatica

Authors: Oliver Kudlacek, Yaprak Dönmez and Thomas Stockner

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A76

Content type: Meeting abstract Published on: 17 September 2012
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The influence of alpha-melanocortin enantiomers on acetaminophen-induced hepatis in mice

Authors: Petra Turčić, Karlo Houra, Mirna Bradamante, Paško Konjevoda, Tomislav Kelava and Nikola Štambuk

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A77

Content type: Meeting abstract Published on: 17 September 2012
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The NBD-NBD interface is not the sole determinant for transport in ABC transporters

Authors: Yaprak Dönmez, Zahida Parveen, Peter Chiba and Thomas Stockner

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A78

Content type: Meeting abstract Published on: 17 September 2012
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Activity of semicarbazide-sensitive amine oxidase in guinea-pig tissues is not affected by metformin

Authors: Katja Lukan and Simona Rajtar Osredkar

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A79

Content type: Meeting abstract Published on: 17 September 2012
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Real-time uptake of fluorescent ASP+ via the organic cation transporter 3

Authors: Felix P Mayer, Diethart Schmid, Marion Holy, Jae-Won Yang, Isabella Salzer, Stefan Boehm, Peter Chiba and Harald H Sitte

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A80

Content type: Meeting abstract Published on: 17 September 2012
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Restricted collision coupling of the adenosine A_2Areceptor is due to its agonist-induced confinement in the membrane

Authors: Patrick Thurner, Simon Keuerleber, Ingrid Gsandtner, Christoph Gruber, Michael Freissmuth and Jürgen Zezula

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A81

Content type: Meeting abstract Published on: 17 September 2012
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NKP-1339, a first-in-class anticancer drug showing mild side effects and activity in patients suffering from advanced refractory cancer

Authors: Robert Trondl, Petra Heffeter, Michael A Jakupec, Walter Berger and Bernhard K Keppler

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A82

Content type: Meeting abstract Published on: 17 September 2012
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TRPC3 overexpression promotes angiotensin II-induced cardiac dysfunction

Authors: Bernhard Doleschal, Stefan Wolf, Marie-Sophie Huber, Gerald Wölkart, Gudrun Antoons and Klaus Groschner

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A83

Content type: Meeting abstract Published on: 17 September 2012
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Axonal transport of botulinum toxin A from periphery to CNS in sensory and motor nerves

Authors: Ivica Matak, Lidija Bach-Rojecky, Boris Filipović, Peter Riederer and Zdravko Lacković

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A84

Content type: Meeting abstract Published on: 17 September 2012
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A TRPC3 blocker, Pyr3, prevents stent-induced arterial remodeling

Authors: Sarah König, Sara Browne, Heinrich Mächler, Gerald Höfler, C Oliver Kappe, Toma N Glasnov, Marlen Braune, Eric Wittchow and Klaus Groschner

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A85

Content type: Meeting abstract Published on: 17 September 2012
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Consumption of serum lipid-reducing drugs in Serbia compared with Scandinavian countries: a population-based study, 2004–2010

Authors: Ana Sabo, Zdenko Tomić, Nebojša Stilinović, Boris Milijašević, Momir Mikov, Saša Vukmirović and Olga Horvat

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A86

Content type: Meeting abstract Published on: 17 September 2012
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Neuropeptide Y modulates fear and fear extinction in distinct nuclei of the amygdala

Authors: Ramon O Tasan, Dilip Verma, Mario Mietzsch, Regine Heilbronn, Herbert Herzog and Günther Sperk

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A87

Content type: Meeting abstract Published on: 17 September 2012
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Plasma nitrite concentrations decrease after hyperoxia-induced oxidative stress in healthy humans

Authors: Darko Modun, Mladen Krnić, Jonatan Vuković, Višnja Kokić, Lea Kukoč-Modun, Dimitrios Tsikas and Zeljko Dujić

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A88

Content type: Meeting abstract Published on: 17 September 2012
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Peptidomics screening for the discovery of uterotonic plant peptides

Authors: Johannes Koehbach, Alfred F Attah, Margaret O’Brien, Michael Freissmuth and Christian W Gruber

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A89

Content type: Meeting abstract Published on: 17 September 2012
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Antiepileptic activity and subtype-selective action of flupirtine at GABA_Areceptors

Authors: Mirnes Bajrić, Felicia Klinger, Ulla Schandl, Helmut Kubista and Stefan Boehm

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A90

Content type: Meeting abstract Published on: 17 September 2012
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Activation of kappa opioid receptors reduces seizure activity in a dose-dependent way

Authors: Luca Zangrandi and Christoph Schwarzer

Citation: BMC Pharmacology and Toxicology 2012 13(Suppl 1):A91

Content type: Meeting abstract Published on: 17 September 2012
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18th Scientific Symposium of the Austrian Pharmacological Society (APHAR)

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