Articles

Page 12 of 21

C-type natriuretic peptide/guanylyl cyclase-B (GC-B) system attenuates proliferation of rhabdomyosarcoma in combination with sildenafil: A novel anticancer therapy

Authors: Masahiro Zenitani, Shuichiro Uehara, Toru Kimura, Takashi Nojiri, Koichi Miura, Hiroshi Hosoda, Mikiya Miyazato, Hiroomi Okuyama and Kenji Kangawa

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A103

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
The role of particulate guanylyl cyclase B (GC-B) in auditory function in adult mice

Authors: Steffen Wolter, Dorit Möhrle, Dennis Zelle, Marlies Knipper, Hannes Schmidt and Lukas Rüttiger

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A102

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Interaction of cCMP with the cGK, cAK and MAPK kinases in murine tissues

Authors: Stefanie Wolfertstetter, Frank Schwede, Franz Hofmann and Jens Schlossmann

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A101

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Identification of new inhibitors of soluble guanylyl cyclase activity

Authors: Jagamya Vijayraghavan and Focco van den Akker

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A95

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Linaclotide-induced electrolyte secretion in human and rat colon: Ussing chamber studies

Authors: Boris Tchernychev, Gerhard Hannig, David Arthur, Pei Ge, Jenny Tobin and Inmaculada Silos-Santiago

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A94

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Influence of smoking on vascular reactivity to cGMP generators in human internal thoracic arteries

Authors: Masashi Tawa, Takeshi Kinoshita, Tohru Asai, Tomoaki Suzuki, Takeshi Imamura and Tomio Okamura

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A93

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Direct visualization of cGMP microdomains in adult cardiomyocytes

Authors: Hariharan Subramanian, Alexander Froese, Daniela Hübscher, Konrad R Götz and Viacheslav O Nikolaev

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A91

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Effect of soluble guanylyl cyclase activator and stimulator therapy on nitroglycerin-induced nitrate tolerance in rats

Authors: P Stamm, A Jabs, M Oelze, Y Mikhed, S Kröller-Schön, P Welschof, T Jansen, M Hausding, M Kopp, S Steven, E Schulz, J-P Stasch, T Münzel and A Daiber

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A90

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Snake venom natriuretic peptides: Potential molecular probes

Authors: Sindhuja Sridharan and R Manjunatha Kini

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A87

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
IWP-121: a novel sGC stimulator that reduces blood pressure and exhibits anti-fibrotic and anti-inflammatory activities in the Dahl Salt-Sensitive rat model

Authors: Courtney Shea, Sheila Ranganath, Guang Liu, Derek Wachtel, Peter Germano, Jenny Tobin, Ping Zhang, Samuel Rivers, G-Yoon Jamie Im, James Sheppeck II and Jaime Masferrer

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A86

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Tadalafil protects from doxorubicin-induced heart failure by attenuating PKG Iα disulfide dimerisation

Authors: Oleksandra Prysyazhna, Joseph R Burgoyne and Philip Eaton

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A75

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Functions of NO-GC1 and NO-GC2 in pain processing

Authors: Jonas Petersen, Evanthia Mergia, Oliver Drees, Ruirui Lu, Catherine Real, Andreas Friebe, Doris Koesling and Achim Schmidtko

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A74

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
NMR study of a soluble Guanylate Cyclase (sGC) human homologue: the H-NOX domain from Nostoc sp.

Authors: Aikaterini Argyriou, Marina Bantzi, Athanassios Giannis, Andreas Papapetropoulos and Georgios A Spyroulias

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A73

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
The world's first clinical randomized trial of atrial natriuretic peptide for preventing cancer recurrence following lung cancer surgery

Authors: Takashi Nojiri, Hiroshi Hosoda, Takeshi Tokudome, Toru Kimura, Meinoshin Okumura and Kenji Kangawa

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A72

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Enhancement of cAMP-mediated inotropic responses by CNP is regulated differently by PDE2 in normal and failing hearts

Authors: Silja Meier, Kjetil Wessel Andressen, Jan Magnus Aronsen, Ivar Sjaastad, Tor Skomedal, Jan-Bjørn Osnes, Eirik Qvigstad, Finn Olav Levy and Lise Román Moltzau

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A66

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Rational design of a PKA-based sensor for cGMP

Authors: Robin Lorenz, Daniel He, Choel Kim, Chinten J Lim and Friedrich W Herberg

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A64

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Cyclic GMP Dependent Protein Kinase (PKG) as a mediator of EGFR-Induced Apoptosis in Breast Cancer

Authors: Nicole M Jackson and Brian P Ceresa

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A60

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
The sGC-stimulator Riociguat for the treatment of Raynaud's phenomenon: A single-dose, double-blind, randomized, placebo-controlled cross-over study (DIGIT)

Authors: Michael Huntgeburth, Johannes Kießling, Gerrit Weimann, Verena Kiepsel, Soundos Saleh, Nicolas Hunzelmann and Stephan Rosenkranz

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A58

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Cell-specific modulation of gastrointestinal NO-induced relaxation by phosphodiesterases

Authors: Dieter Groneberg, Annemarie Aue, Barbara Lies and Andreas Friebe

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A56

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
NO-dependent cGMP signalling in neurons and astrocytes

Authors: Jan Giesen, Ernst-Martin Füchtbauer, Doris Koesling and Michael Russwurm

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A55

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Concomitant administration of sGC stimulators with common classes of anti-hypertensive agents results in increased efficacy in spontaneously hypertensive rats

Authors: Peter Germano, Jenny Tobin, Robert Jefferson, Courtney Shea, Adaline Smith, G-Yoon Jamie Im, James Sheppeck II, James Wakefield, Kristie Sykes, Maria Ribadeneira, Samuel Rivers and Jaime Masferrer

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A54

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Erythrocytes do not produce biologically active NO

Authors: Stepan Gambaryan, Igor Mindukshev, Natalia Rukoyatkina, Iraida Sharina, Emil Martin and Ulrich Walter

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A53

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Modulation of cGMP/cAMP crosstalk on the level of PDE3 in animals lacking NO-sensitive guanylyl cyclase

Authors: Andreas Friebe, Sarah Dünnes, Viacheslav Nikolaev, Barbara Lies and Dieter Groneberg

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A52

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
A CNP-cGMP-cGKI-MAPK pathway promotes melanoma growth in vitro and in vivo in mice

Authors: Sandeep Dhayade, Susanne Feil, Anja Ulmer, Susanne Kaesler, Tobias Sinnberg, Martin Thunemann, Ulrike Naumann, Tilo Biedermann, Birgit Schittek and Robert Feil

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A49

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Design and directed evolution of genetically encoded cGMP sensors

Authors: Arne Fabritius and Oliver Griesbeck

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A48

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Arterial stiffness and collagen expression in mice lacking NO-sensitive guanylyl cyclase

Authors: Sarah Dünnes, Dieter Groneberg, Volker Herold, Peter Jakob and Andreas Friebe

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A46

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
The predator odor 2,4,5-trimethylthiazoline binds and activates receptor guanylyl cyclase-G to elicit innate defensive responses

Authors: Ying-Chi Chao and Ruey-Bing Yang

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A40

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
A systems biology approach to cGMP suggests a prominent role for sGC in stroke: Validation by mechanism-based activation of apo-sGC in non-steal dosing coveys neuroprotection and increased survival

Authors: Ana I Casas, Friederike Langhauser, Vu Thao-Vi Dao, Emre Guney, Pamela WM Kleikers, Manuela García López, Jörg Menche, Albert-László Barabási, Christoph Kleinschnitz and Harald HHW Schmidt

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A39

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Circulating Atrial Natriuretic Peptide Genetic Association Study Identifies a Novel Gene Cluster Associated with Reduced NT-proANP, Increased Stroke and Higher Diastolic Blood Pressure

Authors: Naveen L Pereira, Nirubol Tosakulwong, Christopher G Scott, Gregory D Jenkins, Naresh Prodduturi, Yubo Chai, Timothy M Olson, Richard J Rodeheffer, Margaret M Redfield MD, Richard M Weinshilboum and John C Burnett Jr.

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A37

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
A case of chaos? NO causes arrhythmic motor pattern via interstitial cells of Cajal in the murine colon

Authors: Katharina Beck, Dieter Groneberg, Andreas Friebe and Barbara Lies

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A36

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Anemia of cGKI deficient mice is caused by intestinal bleeding

Authors: Elisabeth Angermeier, Katrin Domes and Franz Hofmann

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A35

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Investigation of the role of multidrug resistance proteins (MRPs) in vascular homeostasis

Authors: Robert M H Allen, Aniruthan Renukanthan, Kristen J Bubb, Inmaculada C Villar, Amie J Moyes, Reshma S Baliga and Adrian J Hobbs

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A33

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Hormone suppression silencing GUCY2C is required for colorectal cancer

Authors: Scott A Waldman

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A31

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Pivotal vascular homeostatic role for endothelium-derived C-type natriuretic peptide (CNP)

Authors: Adrian J Hobbs

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A27

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
The cyclic nucleotide 3’,5’-cIMP produced by sGC is a second messenger in the vascular wall

Authors: Paul M Vanhoutte, Susan WS Leung and Yuansheng Gao

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A25

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Antifibrotic function of cGKI in the kidney

Authors: Jens Schlossmann, Elisabeth Schinner, Veronika Wetzll, Lothar Faerber and Franz Hofmann

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A23

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Mechanism and protective properties of S-nitrosation by nitric oxide in cardiac mitochondria

Authors: Thomas Krieg

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A21

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Ultrasensitive signal detection by a guanylyl cyclase chemoreceptor

Authors: U Benjamin Kaupp

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A20

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Inhibition of cGMP-metabolizing PDEs as target for cognitive enhancement

Authors: Holger Rosenbrock

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A19

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Targeting cyclic nucleotides in CNS drug discovery: a translational approach into cognition enhancement

Authors: Jos Prickaerts

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A18

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
New insights into leveraging PKG signalling to treat diseased hearts

Authors: Dong ik Lee, Taishi Nakamura and David A. Kass

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A17

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
cGMP and cAMP pathways rearrange ARHGAP17 and ARHGEF6 protein complexes to control Rac1 in platelets

Authors: Zoltan Nagy, Kieran Wynne, Alexander von Kriegsheim, Stepan Gambaryan and Albert Smolenski

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A16

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Roles of 8-nitro-cGMP in autophagy regulation

Authors: Hirokazu Arimoto

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A14

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Using PDE5 inhibitors for the prevention and treatment of colorectal cancer

Authors: Darren D Browning

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A11

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Gene therapy approaches to restore retinal cGMP channel function

Authors: Martin Biel

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A9

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Natriuretic peptides and cGMP in metabolic disease

Authors: Sheila Collins

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A7

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
Stimulation of soluble guanylyl cyclase protects against obesity by recruiting brown adipose tissue

Authors: Alexander Pfeifer, Jennifer Etzrodt and Linda S Hoffmann

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A6

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
The discovery and characterization of novel soluble guanylate cyclase stimulators

Authors: Jaime L Masferrer

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A5

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
MANP: a novel particulate guanylyl cyclase A receptor/cGMP activator for resistant hypertension: preliminary first in human clinical trial results

Authors: John C Burnett Jr, Paul McKie, Denise Heublein, Brenda Huntley, Horng Chen, Valentina Cannone, Alessia Buglioni and Daniel McCormick

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A3

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF
LCZ696 (sacubitril/valsartan), an angiotensin receptor neprilysin inhibitor (ARNI): clinical development in heart failure

Authors: Martin P Lefkowitz

Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A1

Content type: Meeting abstract Published on: 2 September 2015

This article is part of a Supplement: Volume 16 Supplement 1
- View Full Text
- View PDF

Reviewer acknowledgments

Articles

Important information

Annual Journal Metrics

Peer-review Terminology

Follow

BMC Pharmacology and Toxicology

Contact us