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  1. Electronic cigarettes (e-cigs) have recently become very popular particularly among the younger generation. These nicotine delivery devices are viewed as a preferable alternative to more conventional forms of ...

    Authors: Daniel Panitz, Harsha Swamy and Keith Nehrke
    Citation: BMC Pharmacology and Toxicology 2015 16:32
  2. Biphasic immediate-release (IR)/extended-release (ER) hydrocodone bitartrate (HB)/acetaminophen (APAP) 7.5/325-mg tablets are formulated with gastroretentive ER drug delivery technology that has been associate...

    Authors: Krishna Devarakonda, Kenneth Kostenbader, Michael J. Giuliani and Jim L. Young
    Citation: BMC Pharmacology and Toxicology 2015 16:31
  3. Wilson disease (WD) is an autosomal recessive disorder of human copper metabolism characterized by copper accumulation in the liver due to impaired excretion of copper into the bile. Brain accumulation of copp...

    Authors: Salih Boga, Dhanpat Jain and Michael L. Schilsky
    Citation: BMC Pharmacology and Toxicology 2015 16:30
  4. Glucagon nasal powder (GNP), a novel intranasal formulation of glucagon being developed to treat insulin-induced severe hypoglycemia, contains synthetic glucagon (10 % w/w), beta-cyclodextrin, and dodecylphosphoc...

    Authors: Frederick E. Reno, Patrick Normand, Kevin McInally, Sherwin Silo, Patricia Stotland, Myriam Triest, Dolores Carballo and Claude Piché
    Citation: BMC Pharmacology and Toxicology 2015 16:29
  5. Despite the public health relevance of analgesic use, large-scale studies on this topic in Germany are lacking. This study describes the prevalence, trends, associations and patterns of use of prescription and...

    Authors: Giselle Sarganas, Amanda K. Buttery, Wanli Zhuang, Ingrid-Katharina Wolf, Daniel Grams, Angelika Schaffrath Rosario, Christa Scheidt-Nave and Hildtraud Knopf
    Citation: BMC Pharmacology and Toxicology 2015 16:28
  6. Gloriosa superba (GSb) is a highly poisonous plant and its toxicity is due to anti-mitotic effects of constituents such as colchicine and gloriosine on rapidly proliferating cells. Poisoning is known to cause ver...

    Authors: Ranjan Premaratna, Mindu S. Weerasinghe, Nuwan. P. Premawardana and H Janaka de Silva
    Citation: BMC Pharmacology and Toxicology 2015 16:27
  7. Human antibacterial exposure occur in different ways including consumption of animal and agricultural products as well as use of prescribed and non-prescribed agents. We estimated the prevalence and explored t...

    Authors: Moses Ocan, Yukari C. Manabe, Hannington Baluku, Esther Atukwase, Jasper Ogwal-Okeng and Celestino Obua
    Citation: BMC Pharmacology and Toxicology 2015 16:26
  8. The innate immune receptor RIG-I detects viral RNA within the cytosol of infected cells. Activation of RIG-I leads to the induction of antiviral cytokines, in particular type I interferon, the inhibition of a ...

    Authors: Martin Coenen, Annette Viktoria Hinze, Martin Mengel, Christine Fuhrmann, Bastian Lüdenbach, Julian Zimmermann, Verena Dykstra, Rolf Fimmers, Roberto Viviani, Julia Stingl, Stefan Holdenrieder, Marcus Müller, Gunther Hartmann and Christoph Coch
    Citation: BMC Pharmacology and Toxicology 2015 16:25
  9. Phosphatidylserine-containing liposomes (PSL) have been shown to reduce inflammation in experimental models of acute arthritis, by mimicking the apoptotic process. The aim of this study was to evaluate the eff...

    Authors: Paulo CM Urbano, Vanete T. Soccol, Vivian N. Teixeira, Patrícia G. Oliveira, Lidiane I. Filippin, Wagner H. Bonat, Carolina de Oliveira, Gustavo R. Rossi, Ricardo M. Xavier and Valderilio F. Azevedo
    Citation: BMC Pharmacology and Toxicology 2015 16:24
  10. Inability to predict the therapeutic effect of a drug in individual pain patients prolongs the process of drug and dose finding until satisfactory pharmacotherapy can be achieved. Many chronic pain conditions ...

    Authors: Andreas Siegenthaler, Jürg Schliessbach, Pascal H. Vuilleumier, Peter Juni, Hanns U. Zeilhofer, Lars Arendt-Nielsen and Michele Curatolo
    Citation: BMC Pharmacology and Toxicology 2015 16:23
  11. Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease worldwide. Renin-angiotensin system (RAS) inhibitors are the first-line treatment for diabetic patients with hypertension. However,...

    Authors: Hiroki Miyazaki, Akira Babazono, Takumi Nishi, Toshiki Maeda, Takuya Imatoh, Masayoshi Ichiba and Hiroshi Une
    Citation: BMC Pharmacology and Toxicology 2015 16:22
  12. Authors: Courtney Shea, Sheila Ranganath, Guang Liu, Derek Wachtel, Peter Germano, Jenny Tobin, Ping Zhang, Samuel Rivers, G-Yoon Jamie Im, James Sheppeck II and Jaime Masferrer
    Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A86

    This article is part of a Supplement: Volume 16 Supplement 1

  13. Authors: Silja Meier, Kjetil Wessel Andressen, Jan Magnus Aronsen, Ivar Sjaastad, Tor Skomedal, Jan-Bjørn Osnes, Eirik Qvigstad, Finn Olav Levy and Lise Román Moltzau
    Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A66

    This article is part of a Supplement: Volume 16 Supplement 1

  14. Authors: Michael Huntgeburth, Johannes Kießling, Gerrit Weimann, Verena Kiepsel, Soundos Saleh, Nicolas Hunzelmann and Stephan Rosenkranz
    Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A58

    This article is part of a Supplement: Volume 16 Supplement 1

  15. Authors: Peter Germano, Jenny Tobin, Robert Jefferson, Courtney Shea, Adaline Smith, G-Yoon Jamie Im, James Sheppeck II, James Wakefield, Kristie Sykes, Maria Ribadeneira, Samuel Rivers and Jaime Masferrer
    Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A54

    This article is part of a Supplement: Volume 16 Supplement 1

  16. Authors: Ana I Casas, Friederike Langhauser, Vu Thao-Vi Dao, Emre Guney, Pamela WM Kleikers, Manuela García López, Jörg Menche, Albert-László Barabási, Christoph Kleinschnitz and Harald HHW Schmidt
    Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A39

    This article is part of a Supplement: Volume 16 Supplement 1

  17. Authors: Steven S Pullen, Kathleen A Lincoln, Paul C Harrison, Hongxing Chen, Hong Wang, Holly Clifford, HuSheng Qian, Diane Wong, Chris Sarko, Jehrod Brenneman, Ryan Fryer, Jeremy Richman, Glenn A Reinhart and Carine Boustany
    Citation: BMC Pharmacology and Toxicology 2015 16(Suppl 1):A4

    This article is part of a Supplement: Volume 16 Supplement 1

Reviewer acknowledgments

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