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  1. The new European pharmacovigilance legislation has been suggested as marking the beginning of a new chapter in drug safety, making patients an important part of pharmacovigilance. In Sweden since 2008 it has b...

    Authors: Andreas Vilhelmsson, Tommy Svensson, Anna Meeuwisse and Anders Carlsten
    Citation: BMC Pharmacology and Toxicology 2012 13:19
  2. To examine the efficacy of lisdexamfetamine dimesylate (LDX) in adults with attention-deficit/hyperactivity disorder (ADHD) who remained symptomatic (ADHD Rating Scale IV [ADHD-RS-IV] total score >18) on amphe...

    Authors: Thomas Babcock, Bryan Dirks, Ben Adeyi and Brian Scheckner
    Citation: BMC Pharmacology and Toxicology 2012 13:18
  3. Occupational and environmental exposures to lead remain a public health problem as lead alters physiological processes by inducing oxidative stress and mimicking divalent cations. This study was designed to in...

    Authors: Oluseyi C Ayinde, Sunday Ogunnowo and Rita A Ogedegbe
    Citation: BMC Pharmacology and Toxicology 2012 13:17
  4. Chronic Obstructive Pulmonary Disease (COPD) is a disease characterized by a largely irreversible airflow obstruction and a persistent, excessive inflammatory response. Alveolar macrophages (AMs) are increased...

    Authors: Marianne Jennifer Ratcliffe and Iain Gordon Dougall
    Citation: BMC Pharmacology and Toxicology 2012 13:15
  5. The objectives of the current study were to determine amikacin pharmacokinetics in patients undergoing treatment with continuous venovenous haemodiafiltration (CVVHDF) in an Intensive Care Unit (ICU), and to d...

    Authors: Deirdre M D’Arcy, Eoin Casey, Caitriona M Gowing, Maria B Donnelly and Owen I Corrigan
    Citation: BMC Pharmacology and Toxicology 2012 13:14
  6. Our previous studies suggest silkworms can be used as model animals instead of mammals in pharmacologic studies to develop novel therapeutic medicines. We examined the usefulness of the silkworm larvae Bombyx mor...

    Authors: Yoshinori Inagaki, Yasuhiko Matsumoto, Keiko Kataoka, Naoya Matsuhashi and Kazuhisa Sekimizu
    Citation: BMC Pharmacology and Toxicology 2012 13:13
  7. Cocaine exposure has been reported to alter central μ-opioid receptor (MOR) expression in vivo. The present study employed an in vitro cellular model to explore possible mechanisms that may be involved in this ac...

    Authors: Warren Winick-Ng, Francesco Leri and Bettina E Kalisch
    Citation: BMC Pharmacology and Toxicology 2012 13:11
  8. The widespread use of natural health products is also a problem, as they could interact with prescribed drugs in patients. One commonly used product is glucosamine for osteoarthritis and some reports have foun...

    Authors: Robert Eggertsen, Åke Andreasson and Lennart Andrén
    Citation: BMC Pharmacology and Toxicology 2012 13:10
  9. The disappointing clinical failures of five topical vaginal microbicides have provided new insights into factors that impact microbicide safety and efficacy. Specifically, the greater risk for human immunodefi...

    Authors: Karissa Lozenski, Robert Ownbey, Brian Wigdahl, Tina Kish-Catalone and Fred C Krebs
    Citation: BMC Pharmacology and Toxicology 2012 13:9
Reviewer acknowledgments

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