Figure 3

Maximal endothelial NO and ONOO ^- concentrations, and [NO]/[ONOO ^- ] ratio stimulated with nebivolol, L-755,507, 2-MeSATP, and ATP. (A) Maximal NO and ONOO^- concentration release from HUVECs stimulated with nebivolol, L-755,507, 2-MeSATP, and ATP (each at 1 μM). Values are mean ± SD (n = 5). One-way ANOVA, Student-Newman-Keuls multiple comparison post-hoc test: *P < 0.05 compared with either the maximal NO or ONOO^- concentration released by cells stimulated with nebivolol. (B) The [NO]/[ONOO^-] ratio calculated from the maximal concentration in A. Values are mean ± SD (n = 5). One-way ANOVA, Student-Newman-Keuls multiple comparison post-hoc test: *P < 0.05 compared with [NO]/[ONOO^-] ratio calculated for nebivolol.