Table 2 Baseline individual factors associated with antihypertensive drug changes, CoLaus study
From: Antihypertensive drug treatment changes in the general population: the colaus study
Continuers | Combiners | Switchers | Discontinuers | p-value | |
|---|---|---|---|---|---|
N | 420 (54.4) | 208 (26.9) | 98 (12.7) | 46 (6.0) | |
Women (%) | 213 (50.7) | 93 (44.7) | 50 (51.0) | 15 (32.6) | 0.08 |
Age (years) | 60.2 ± 9.0 | 61.2 ± 8.9 | 59.2 ± 10.1 | 57.7 ± 8.2 | 0.06 |
Educational status (%) | |||||
Basic | 94 (22.4) | 46 (22.1) | 22 (22.5) | 10 (21.7) | |
Apprenticeship | 186 (44.3) | 90 (43.3) | 37 (37.8) | 18 (39.1) | 0.90 |
High school/college | 91 (21.7) | 47 (22.6) | 26 (26.5) | 9 (19.6) | |
University | 49 (11.7) | 25 (12.0) | 13 (13.3) | 9 (19.6) | |
Smoking status (%) | |||||
Never | 169 (40.2) | 75 (36.1) | 43 (43.9) | 19 (41.3) | |
Former | 160 (38.1) | 94 (45.2) | 35 (35.7) | 18 (39.1) | 0.67 |
Current | 91 (21.7) | 39 (18.8) | 20 (20.4) | 9 (19.6) | |
Physically active (%) | 205 (48.8) | 100 (48.1) | 56 (57.1) | 26 (56.5) | 0.34 |
BMI (kg/m2) | 28.4 ± 4.9 | 29 ± 4.4 | 27.9 ± 4.9 | 27.7 ± 4.2 | 0.15 |
BMI categories (%) | |||||
Normal | 105 (25.0) | 36 (17.3) | 29 (29.6) | 12 (26.1) | |
Overweight | 181 (43.1) | 92 (44.2) | 41 (41.8) | 26 (56.5) | <0.05 |
Obese | 134 (31.9) | 80 (38.5) | 28 (28.6) | 8 (17.4) | |
Waist (cm) | 97 ± 14 | 99 ± 14 | 95 ± 13 | 96 ± 12 | 0.13 |
Abdominal obesity (%) | 219 (52.1) | 121 (58.2) | 48 (49.0) | 16 (34.8) | <0.05 |
Alcohol drinker (%) | 301 (71.7) | 160 (76.9) | 74 (75.5) | 31 (67.4) | 0.39 |
Personal history of (%) | |||||
Myocardial infarction | 27 (6.4) | 16 (7.7) | 2 (2.0) | 1 (2.2) | NA |
Stroke | 11 (2.6) | 8 (3.9) | 5 (5.1) | 1 (2.2) | NA |
CVD | 52 (12.4) | 35 (16.8) | 11 (11.2) | 6 (13.0) | 0.41 |
Dyslipidemia | 182 (43.3) | 105 (50.5) | 39 (39.8) | 19 (41.3) | 0.23 |
Diabetes | 64 (15.2) | 31 (14.9) | 10 (10.2) | 4 (8.7) | 0.41 |
Family history of (%) | |||||
Myocardial infarction | 110 (26.2) | 44 (21.2) | 26 (26.5) | 14 (30.4) | 0.43 |
Stroke | 88 (21.0) | 35 (16.8) | 23 (23.5) | 10 (21.7) | 0.51 |
Hypertension | 200 (47.6) | 106 (51.0) | 49 (50.0) | 27 (58.7) | 0.51 |
Dyslipidemia | 72 (17.1) | 41 (19.7) | 19 (19.4) | 12 (26.1) | 0.48 |
Diabetes | 85 (20.2) | 44 (21.2) | 20 (20.4) | 12 (26.1) | 0.83 |
Number of other drugs §§ | 2.9 ± 2.4 | 3.1 ± 2.5 | 3.0 ± 2.2 | 2.7 ± 2.7 | 0.80 |