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Table 3 Observed and predicted IPA over time

From: Population pharmacokinetic and pharmacodynamic modeling of transformed binary effect data of triflusal in healthy Korean male volunteers: a randomized, open-label, multiple dose, crossover study

Time

Number of subjects

Number of observed IPA (%)

Number of predicted IPA (%)

0 h

34

1 (3%)

0 (0%)

24 h

34

2 (6%)

2 (6%)

48 h

34

11 (32%)

11 (32%)

96 h

34

29 (85%)

25 (74%)

144 h

34

25 (74%)

28 (82%)

168 h

34

27 (79%)

30 (88%)

192 h

34

30 (88%)

30 (88%)

196 h

34

34 (100%)

34 (100%)

202 h

34

34 (100%)

34 (100%)

216 h

34

28 (82%)

30 (88%)

  1. IPA, inhibition of platelet aggregation.