Skip to main content

Table 3 Summary of statistical analysis of fed/fasted comparison (Study 2)

From: The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756) − a selective CXCR2 antagonist − in healthy adult subjects

 

Danirixin 100 mg Fed

Danirixin 100 mg Fasted

Treatment Difference(Fed vs. Fasted)

 

n

Adjusted Geometric Mean(SE Logs)

n

Adjusted Geometric Mean(SE Logs)

Estimate

90 % CI

AUC (0-∞)(ng h/mL)

15

12,635 (0.082)

13

15,047 (0.088)

0.840

(0.684, 1.031)

Cmax(ng/mL)

16

1411 (0.076)

15

2239 (0.078)

0.630

(0.523, 0.758)