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Table 4 Cellular accumulation ratio values for inhibition studies

From: Intracellular accumulation of Praziquantel in T lymphoblastoid cell lines, CEM (parental) and CEMvbl(P-gp-overexpressing)

Sample

CEM SQV

CEMSQV PZQ

CEMSQV XR

VBL SQV

VBL SQV PZQ

VBL SQV XR

1

0.57

0.45

0.55

0.07

0.08

0.53

2

0.50

0.57

0.51

0.10

0.07

0.50

3

0.59

0.59

0.73

0.10

0.13

0.69

4

0.44

0.53

0.66

0.11

0.13

0.52

Mean

0.52

0.54

0.61

0.09

0.10

0.56

STDEV

0.068

0.061

0.102

0.015

0.031

0.089

p value

 

p = 0.77

p = 0.34

 

p = 0.89

p = 0.03

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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