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Fig. 1 | BMC Pharmacology and Toxicology

Fig. 1

From: Glucagon-like peptide receptor agonists attenuate advanced glycation end products-induced inflammation in rat mesangial cells

Fig. 1

L-165,041 attenuates AGE-induced interleukin-6 (IL-6) production in rat mesangial cells. ELISA was used to measure IL-6 concentrations in cell culture supernatants. a AGE stimulated IL-6 production with a dose-dependent manner. A concentration of 200 μM of AGE was chosen for following experiments. b The AGE-induced IL-6 production was inhibited L-165,041 with a dose-dependent manner. A concentration of 1 μM was chosen for following experiments. (N = 6) *P < 0.05 when compared to control. +P < 0.05 when compared to AGE group

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