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Table 3 DEGs in the GO term of cellular response to leukemia inhibitory factor

From: Identification of potential pathways and microRNA-mRNA networks associated with benzene metabolite hydroquinone-induced hematotoxicity in human leukemia K562 cells

Gene name

Description

C

HQ

Log2 (HQ/C)

Adjusted P-value

INA

internexin neuronal intermediate filament protein alpha

8

25

1.71

0.003***

NEFH

neurofilament heavy polypeptide

201

429

1.10

0.000***

BCLAF1

BCL2 associated transcription factor 1

868

1692

0.96

0.000***

TWISTNB

TWIST neighbor

232

448

0.95

0.009**

NUP35

nucleoporin 35

119

217

0.87

0.001***

ARID5B

AT-rich interaction domain 5B

51

93

0.87

0.002***

WDR35

WD repeat domain 35

138

242

0.80

0.000***

MRPL15

mitochondrial ribosomal protein L15

750

1194

0.67

0.000***

NCL

nucleolin

10,212

16,137

0.66

0.000***

MAT2A

methionine adenosyltransferase 2A

1673

2554

0.61

0.000***

SRM

spermidine synthase

3782

5646

0.58

0.003***

RIF1

replication timing regulatory factor 1

597

890

0.57

0.007**

SRSF3

serine and arginine rich splicing factor 3

4876

7227

0.57

0.000***

CACYBP

calcyclin binding protein

3052

4434

0.54

0.000***

MRAS

muscle RAS oncogene homolog

103

150

0.53

0.031*

HNRNPU

heterogeneous nuclear ribonucleoprotein U

8697

12,532

0.53

0.000***

EED

embryonic ectoderm development

412

585

0.51

0.003***

SRSF7

serine and arginine rich splicing factor 7

2457

3430

0.48

0.000***

PDCD10

programmed cell death 10

609

809

0.41

0.009**

B3GNT2

beta-1,3-N-acetylglucosaminyltransferase 2

468

598

0.35

0.047*

LAPTM5

lysosomal protein transmembrane 5

1844

1483

−0.31

0.040*

KDM3A

lysine demethylase 3A

895

703

−0.35

0.040*

PFKP

phosphofructokinase, platelet

3315

2523

−0.39

0.038*

FZD4

frizzled class receptor 4

331

218

−0.60

0.008**

PARP16

poly (ADP-ribose) polymerase family member 16

496

324

−0.62

0.000***

PCOLCE

procollagen C-endopeptidase enhancer

580

361

−0.68

0.000***

SYNGR1

synaptogyrin 1

693

360

−0.94

0.000***

NR5A2

nuclear receptor subfamily 5 group A member 2

40

20

−1.02

0.024*

CTH

cystathionine gamma-lyase

410

198

−1.05

0.000***

BSPRY

B-box and SPRY domain containing

53

22

−1.27

0.001***

  1. * represents P value < 0.05; ** represents P value < 0.01; *** represents P value < 0.005