Samples | Parameters | Control | Permethrin |
---|
Serum | SALP (U/L) | 53.00 ± 7.82 | 66.80 ± 20.06 |
SGOT (U/L) | 109.75 ± 19.62 | 99.80 ± 10.39 |
SGPT (U/L) | 46.25 ± 7.65 | 44.20 ± 5.01 |
Urine | UUM (mM) | 59.72 ± 5.81 | 46.73 ± 10.65 |
UCRE (mM) | 1902.3 ± 260.8 | 1882.3 ± 322.2 |
- Rats were given permethrin (75 mg/kg body weight/day, gavage) daily for 90 consecutive days. The rats in control group received daily an equivalent dose of corn oil (1 ml/kg body weight/day). After the last administration, 24-hour urine samples of each rat were collected. And then all rats were anesthetized with pentobarbital sodium and decapitated. Blood samples were collected and then centrifuged to obtain the serum for biochemical assays. The biochemical parameters in the samples were analyzed by an automatic analyzer. Data are presented as mean ± SD (n = 5).
- Abbreviations: SALP serum alkaline phosphatase, SGOT serum glutamic-oxaloacetic transaminase, SGPT serum glutamic pyruvic transaminase, UUN urine urea nitrogen, UCRE urine creatine