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Table 2 Liver function test

From: β-Hydroxyphosphocarnitine modifies fibrosis, steatosis and improves liver function in non-alcoholic steatohepatitis induced in rats

Enzyme

Control

β-HPC

NASH

N + β-HPC

AST (U/L)

30.7 ± 2.2

31.7 ± 12.1

101.3 ± 17.3*

77.7 ± 11.9

ALT (U/L)

25.9 ± 8.9

33 ± 9.9

85.7 ± 10.0*

74.3 ± 11.6

ALP (U/L)

127.3 ± 14.8

125.2 ± 29.3

556.4 ± 48.0*

327.4 ± 31.7 *#

GGT (U/L)

0.90 ± 0.1

0.81 ± 0.1

3.21 ± 0.3*

1.00 ± 0.5#

Glucose (U/L)

123.2 ± 50.6

102 ± 33.3

134.3 ± 19.1

118.4 ± 31.7

Triglycerides (mg/dL)

63.7 ± 12.65

38.5 ± 8.74#

255.1 ± 28.49*

48.4 ± 13.40#

Cholesterol (mg/dL)

57.9 ± 8.66

47.5 ± 8.85

42.3 ± 9.46

37.5 ± 7.11

  1. Mean ± SD; experiments were performed in duplicate
  2. *p < 0.05 compared to control group, #p < 0.05 compared to NASH group without treatment. All groups consisted of 5 animals