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Table 2 Comparison of glutamate & GABA levels of male and female treated mice with WIN55, 212–2 in two doses regimen

From: Behavioral, biochemical and histopathological toxic profiles induced by sub-chronic cannabimimetic WIN55, 212–2 administration in mice

 

WIN55, 212–2

0.05 mg/k

(Low dose)

p-value

WIN55, 212–2

0.1 mg/kg

(High dose)

p-value

Group

Male

Female

 

Male

Female

 

Glutamate

0.126 ± 0.022

5.41 ± 4.6

< 0.0001

0.2717 ± 0.01

11.59 ± 4.11

< 0.0001

GABA

7.40 ± 0.23

12.7 ± 1.17

10.1 ± 0.79

23.8 ± 2.21

  1. Independent sample student t- test was carried out, values represent means + SD
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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