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Table 5 Effect of different treatments on liver inflammatory markers (iNOS and COX-2) and arginase levels

From: Berberine-loaded albumin nanoparticles reverse aflatoxin B1-induced liver hyperplasia

Groups/parameters

iNOS (ng/mg protein)

COX-2 (ng/mg protein)

Arginase (ng/mg protein

Sham control

2.05* ± 0.12

0.53* ± 0.05

3.48* ± 0.11

Tween control

2.12* ± 0.02

0.51* ± 0.01

4.45#* ± 0.35

Induction

4.34# ± 0.22

1.18# ± 0.09

0.47# ± 0.17

BER treatment

2.9#* ± 0.01

0.86#* ± 0.01

1.21#* ± 0.08

BER-BSA NPs treatment

2.34#*& ± 0.01

0.63#*& ± 0.03

2.32#*& ± 0.09

  1. Data are represented as mean ± SD, and means with * are statistically significant at p < 0.05 when compared to the induction group, and means with # are statistically significant at p < 0.05 when compared to the control group. Mean with & is statistically significant at p < 0.05 when compared to berberine treatment
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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