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Table 6 Effect of different treatments on the relative expression of p53 and BCL-2 in the liver

From: Berberine-loaded albumin nanoparticles reverse aflatoxin B1-induced liver hyperplasia

Groups/parameters

P53

PTEN

H19

IGF-2

Tween control

1.93* ± 0.013

5.20* ± 0.08

0.32* ± 0.06

1.13* ± 0.06

Induction

0.18* ± 0.03

0.11* ± 0.06

2.67* ± 0.17

3.54* ± 0.058

BER treatment

0.93* ± 0.011

2.62* ± 0.028

1.64* ± 0.05

2.11* ± 0.058

BER-BSA NPs treatment

1.05*& ± 0.03

3.47*& ± 0.11

0.09*& ± 0.01

1.27*& ± 0.07

  1. Data are represented as mean ± SD, and means with * are statistically significant at p < 0.05 compared to the induction group. Mean with & is statistically significant at (p < 0.05) compared to berberine treatment