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Table 7 Histological scores in liver

From: Berberine-loaded albumin nanoparticles reverse aflatoxin B1-induced liver hyperplasia

Groups

Sinusoidal dilatation

Vacuolar and hydropic degeneration

Hemorrhage

Mononuclear cells infiltration (Inflammation)

Necrotic hepatocytes

Control

 +  + 

-

-

-

-

Tween control

 +  + 

-

-

-

-

Induction (c-d)

-

 +  +  + 

 +  +  + 

 + 

 +  +  + 

BER treatment

-

-

 +  + 

 +  + 

 + 

BER-BSA NPs treatment

-

 + 

-

-

-

  1.  − No histopathologic change
  2.  + Histopathology in < 20% of fields
  3.  +  + Histopathology in 20 to 60% of fields
  4.  +  +  + Histopathology in > 60% of fields
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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