Table 1 Characteristics of the participants
Baseline characteristics | COPEP population (n = 105) | PLWH (routine TDM) (n = 119) |
|---|---|---|
Median (range) or Number (%) | Median (range) or Number (%) | |
Demographic characteristics | ||
Sex (no.): | ||
Male | 45 (43) | 50 (42) |
Female | 60 (57) | 69 (58) |
Age (year) | 39 (17—67) | 41 (19—78) |
Body weight (kg) | 73 (47—157) | 66 (40—147) |
Height (cm) | 172 (149—192) | 168 (148—190) |
BMI (kg/m2) | 24 (17—49) | 24 (16—51) |
Drug and sampling | ||
Lopinavir dosing (mg): | ||
200 | - | 9 (8) |
300 | - | 1 (1) |
400 | 105 (100) | 85 (71) |
500 | - | 5 (4) |
600 | - | 7 (6) |
800 | - | 10 (8) |
1000 | - | 2 (2) |
Number of samples per patient | 1 (1—1) | 2 (1—8) |
Time after dose (h) | 1.5 (0.07—19) | 10.25 (1.25—29.5) |