Fig. 5
From: Oxidative stress induction by narasin augments doxorubicin’s efficacy in osteosarcoma
NAC rescues narasin-induced oxidative damage and mitochondrial dysfunction in osteosarcoma cells. NAC significantly reverses decreased mitochondrial membrane (A), increased γ-H2AX (B), decreased basal respiration (C) and decreased maximal respiration (D) induced by narasin. Osteosarcoma cells were incubated with and without NAC for 2 h, followed by treatment of narasin. *, p < 0.05 represent significant difference between narasin-treated cells with and without NAC.