Table 7 Absolute and relative weights of organs of female rats treated with AT-533 gel
From: Acute toxicological evaluation of AT-533 and AT-533 gel in Sprague-Dawley rats
Parameters | Control | Blank gel | AT-533 gel |
|---|---|---|---|
Body weight (g) | 231.400 ± 13.683 | 230.960 ± 11.588 | 233.200 ± 12.787 |
Brain | 1.931 ± 0.065 | 1.937 ± 0.061 | 1.865 ± 0.088 |
Heart | 0.980 ± 0.124 | 0.902 ± 0.058 | 0.856 ± 0.089 |
Liver | 7.318 ± 1.267 | 6.619 ± 0.705 | 6.402 ± 0.367 |
Spleen | 0.639 ± 0.090 | 0.687 ± 0.148 | 0.678 ± 0.105 |
Lung | 1.267 ± 0.165 | 1.229 ± 0.125 | 1.173 ± 0.098 |
Kidneys | 1.636 ± 0.211 | 1.660 ± 0.079 | 1.560 ± 0.057 |
Organ-to-body weight ratio (%) | |||
Brain | 0.835 ± 0.022 | 0.840 ± 0.046 | 0.801 ± 0.047 |
Heart | 0.423 ± 0.044 | 0.392 ± 0.038 | 0.367 ± 0.026 |
Liver | 3.153 ± 0.428 | 2.863 ± 0.220 | 2.750 ± 0.185 |
Spleen | 0.276 ± 0.036 | 0.297 ± 0.056 | 0.292 ± 0.051 |
Lung | 0.548 ± 0.067 | 0.534 ± 0.069 | 0.505 ± 0.057 |
Kidneys | 0.705 ± 0.062 | 0.719 ± 0.025 | 0.670 ± 0.033 |