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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: In vitro evaluation of cell viability and expression profile of growth factors in mouse Sertoli cells exposed to Delta-9-tetrahydrocannabinol: a mechanistic insight into the cannabinoid-induced testicular toxicity

Fig. 2

mRNA expression of caspase-3 in THC-exposed TM4 cells. The effect of THC (50 μM) for a duration exposure period of 24-h on caspase-3 gene expression level measured by RT-PCR in TM4 Sertoli cells. Caspase-3 mRNA expression was normalized to β-actin in each sample. THC significantly increased caspase-3 expression level. Data represent the mean ± SEM of three independent experiments (n = 3). Star shows the statistical significance of change between the groups. *p < 0.05 vs. control group (Mann–Whitney U-test)

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