BMC Pharmacology and Toxicology

Featured article: Tolerance to NSAIDS and opioids in the brain

Chronic NSAID administration in the anterior cingulate cortex can produce analgesic effects and chronic administration can result in tolerance. The authors also find that the effects of NSAIDs in the brain are mediated by the opioid system.

Content type: Research article
| 6 March 2019

Histone deacetylase inhibition by Entinostat for the prevention of electrical and structural remodeling in heart failure

Authors: Johanna K. Freundt, Gerrit Frommeyer, Tilmann Spieker, Fabian Wötzel, Jochen Schulze Grotthoff, Jörg Stypmann, Georg Hempel, Michael Schäfers, Andreas H. Jacobs, Lars Eckardt and Philipp S. Lange
Content type: Research article
| 4 March 2019

Dipeptidyl peptidase 4 (DPP-4) inhibitors and cardiovascular outcomes in patients with type 2 diabetes mellitus (T2DM): a systematic review and meta-analysis

Authors: Dan Liu, Biao Jin, Wei Chen and Peng Yun
Content type: Research article
| 15 February 2019

Gastroprotective activity of a novel Schiff base derived dibromo substituted compound against ethanol-induced acute gastric lesions in rats

Authors: Kamelia Saremi, Sima Kianpour Rad, Faezeh Tayeby, Mahmood A. Abdulla, Hamed Karimian and Nazia Abdul Majid
Content type: Research article
| 15 February 2019

Identification of novel candidate indicators for assessing zinc status during pregnancy in mice from microarray data

Authors: Wan Xu, Hongyan Wu and Lixin Shang
Content type: Research article
| 15 February 2019

Burden of paraquat poisoning in the department of Antioquia, Colombia

Authors: Jefferson Antonio Buendía, Gabriel Jaime Restrepo Chavarriaga and Andrés F. Zuluaga

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Content type: Review
| 5 January 2013

A review of the differences and similarities between generic drugs and their originator counterparts, including economic benefits associated with usage of generic medicines, using Ireland as a case study

Authors: Suzanne Dunne, Bill Shannon, Colum Dunne and Walter Cullen
Content type: Case report
| 4 May 2013

Rifampicin-warfarin interaction leading to macroscopic hematuria: a case report and review of the literature

Authors: Maria AP Martins, Adriano MM Reis, Mariana F Sales, Vandack Nobre, Daniel D Ribeiro, Manoel OC Rocha and Antônio LP Ribeiro
Content type: Research article
| 4 October 2013

Physiological and pharmacokinetic effects of oral 1,3-dimethylamylamine administration in men

Authors: Brian K Schilling, Kelley G Hammond, Richard J Bloomer, Chaela S Presley and Charles R Yates
Content type: Commentary
| 16 August 2014

An inevitable wave of prescription drug monitoring programs in the context of prescription opioids: pros, cons and tensions

Authors: M Mofizul Islam and Ian S McRae
Content type: Research article
| 23 April 2013

Pharmaceutical quality of seven generic Levodopa/Benserazide products compared with original Madopar® / Prolopa®

Authors: Urs E Gasser, Anton Fischer, Jan P Timmermans and Isabelle Arnet

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Aims and scope

BMC Pharmacology and Toxicology is an open access, peer-reviewed journal that considers articles on all aspects of chemically defined therapeutic and toxic agents. The journal welcomes submissions from all fields of experimental and clinical pharmacology including clinical trials.It is journal policy to publish work deemed by peer reviewers to be a coherent and sound addition to scientific knowledge and to put less emphasis on interest levels, provided that the research constitutes a useful contribution to the field.

Editor

Benjamin Ragen, BioMed Central

Section Editors

Michael Aschner, Albert Einstein College of Medicine
Phil Biggin, University of Oxford
Lucio Guido Costa, University of Washington
David H Farb, Boston University School of Medicine
Giorgio Palu, University of Padova
Catherine MT Sherwin, University of Utah

Catherine Sherwin, Section Editor

Dr. Catherine Sherwin is currently an Associate Professor

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