BMC Pharmacology and Toxicology

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Drugs and gut microbiome interactions

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In high glucose conditions, the mechanism in which dexamethasone inhibits cellular proliferation and migration in the vascular smooth muscle cells, may be mediated by FAK.

Co-administration of pregabalin and agomelatine for the treatment of chronic lower back pain did not improve patients’ pain scores significantly. However, this combination improved patients' general and mental health significantly.

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GAS-STING signaling plays an essential pathogenetic role in Doxorubicin-Induced Cardiotoxicity

Authors: Zilong Xiao, Ziqing Yu, Chaofeng Chen, Ruizhen Chen and Yangang Su

Content type: Research 24 March 2023
The toxic effects of anabolic steroids “nandrolone decanoate” on cardiac and skeletal muscles with the potential ameliorative effects of silymarin and fenugreek seeds extract in adult male albino rats

Authors: Dalia Abd Elwahab Hassan, Sherien S. Ghaleb, Amr reda Zaki, Ahmed Abdelmenem, Shimaa Nabil and Mostafa Abdallah Abdel Alim

Content type: Research 15 March 2023
miR-34a/DRP-1-mediated mitophagy participated in cisplatin-induced ototoxicity via increasing oxidative stress

Authors: Haiyan Wang, Hanqing Lin, Weibiao Kang, Lingfei Huang, Sisi Gong, Tao Zhang, Xiaotong Huang, Feinan He, Yongyi Ye, Yiyang Tang, Haiying Jia and Haidi Yang

Content type: Research 7 March 2023
Medication-induced osteonecrosis of the jaw: a review of cases from the Food and Drug Administration Adverse Event Reporting System (FAERS)

Authors: Hardeep S. Ahdi, Thomas Adam Wichelmann, Sasirekha Pandravada and Eli D. Ehrenpreis

Content type: Research article 6 March 2023
Pharmacokinetics and safety of two Voriconazole formulations after intravenous infusion in two doses in healthy Chinese subjects

Authors: Xin Li, Chenjing Wang, Ping Shi, Yanping Liu, Ye Tao, Pingping Lin, Ting Li, Haixun Hu, Feifei Sun, Shuqin Liu, Yao Fu and Yu Cao

Content type: Research 3 March 2023

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A review of the differences and similarities between generic drugs and their originator counterparts, including economic benefits associated with usage of generic medicines, using Ireland as a case study

Authors: Suzanne Dunne, Bill Shannon, Colum Dunne and Walter Cullen

Content type: Review 5 January 2013
Deflazacort: therapeutic index, relative potency and equivalent doses versus other corticosteroids

Authors: Luca Parente

Content type: Debate 5 January 2017
A case report of zinc phosphide poisoning: complicated by acute renal failure and tubulo interstitial nephritis

Authors: Nilukshana Yogendranathan, H. M. M. T. B. Herath, Thenuka Sivasundaram, R. Constantine and Aruna Kulatunga

Content type: Case report 25 May 2017
Rosacea-like facial rash related to metformin administration in a young woman

Authors: Laura Mumoli, Antonio Gambardella, Angelo Labate, Elena Succurro, Giovambattista De Sarro, Franco Arturi and Luca Gallelli

Content type: Case report 8 February 2014
Pregabalin induced visual hallucinations – a rare adverse reaction

Authors: Georgios Mousailidis, Basavaraja Papanna, Andrew Salmon, Aung Sein and Qutaiba Al-Hillawi

Content type: Case report 28 February 2020

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Aims and scope

BMC Pharmacology and Toxicology is an open access, peer-reviewed journal that considers articles on all aspects of chemically defined therapeutic and toxic agents. The journal welcomes submissions from all fields of experimental and clinical pharmacology including clinical trials and toxicology.

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