BMC Pharmacology and Toxicology

Featured article: Tolerance to NSAIDS and opioids in the brain

Chronic NSAID administration in the anterior cingulate cortex can produce analgesic effects and chronic administration can result in tolerance. The authors also find that the effects of NSAIDs in the brain are mediated by the opioid system.

Content type: Research article
| 16 October 2018

Artesunate may inhibit liver fibrosis via the FAK/Akt/β-catenin pathway in LX-2 cells

Authors: Jian Lv, Ruidan Bai, Li Wang, Jiefang Gao and Hong Zhang
Content type: Research article
| 10 October 2018

Poisonings in Poland reported to the Polish National Health Fund in the years 2009–2011

Authors: Aleksandra Świderska, Marek Wiśniewski, Marek Wiergowski, Anna Krakowiak and Jacek Sein Anand
Content type: Research article
| 10 October 2018

Efficacy and safety of the switch of Triumeq® to generic (abacavir + lamivudine) + Tivicay®: data at 24 weeks

Authors: Julián Olalla, Javier Pérez-Stachowski, Begoña Tortajada, Alfonso Del Arco, Efrén Márquez, Javier De la Torre, Miriam Nieto, José María García de Lomas, José Luis Prada and Javier García-Alegría
Content type: Technical advance
| 5 October 2018

Comparing lethal dose ratios using probit regression with arbitrary slopes

Authors: Chengfeng Lei and Xiulian Sun
Content type: Case report
| 1 October 2018

The critical interaction between valproate sodium and warfarin: case report and review

Authors: Chenguang Zhou, Yi Sui, Weijin Zhao, Chunyao Dong, Li Ren, Pingmei Song, Bing Xu and Xiaohong Sun

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Content type: Review
| 5 January 2013

A review of the differences and similarities between generic drugs and their originator counterparts, including economic benefits associated with usage of generic medicines, using Ireland as a case study

Authors: Suzanne Dunne, Bill Shannon, Colum Dunne and Walter Cullen
Content type: Case report
| 4 May 2013

Rifampicin-warfarin interaction leading to macroscopic hematuria: a case report and review of the literature

Authors: Maria AP Martins, Adriano MM Reis, Mariana F Sales, Vandack Nobre, Daniel D Ribeiro, Manoel OC Rocha and Antônio LP Ribeiro
Content type: Research article
| 4 October 2013

Physiological and pharmacokinetic effects of oral 1,3-dimethylamylamine administration in men

Authors: Brian K Schilling, Kelley G Hammond, Richard J Bloomer, Chaela S Presley and Charles R Yates
Content type: Research article
| 23 April 2013

Pharmaceutical quality of seven generic Levodopa/Benserazide products compared with original Madopar® / Prolopa®

Authors: Urs E Gasser, Anton Fischer, Jan P Timmermans and Isabelle Arnet
Content type: Research article
| 11 December 2013

Ecotoxicology inside the gut: impact of heavy metals on the mouse microbiome

Authors: Jérôme Breton, Sébastien Massart, Peter Vandamme, Evie De Brandt, Bruno Pot and Benoît Foligné

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Aims and scope

BMC Pharmacology and Toxicology is an open access, peer-reviewed journal that considers articles on all aspects of chemically defined therapeutic and toxic agents. The journal welcomes submissions from all fields of experimental and clinical pharmacology including clinical trials.It is journal policy to publish work deemed by peer reviewers to be a coherent and sound addition to scientific knowledge and to put less emphasis on interest levels, provided that the research constitutes a useful contribution to the field.

Editor

Benjamin Ragen, BioMed Central

Section Editors

Michael Aschner, Albert Einstein College of Medicine
Phil Biggin, University of Oxford
Lucio Guido Costa, University of Washington
David H Farb, Boston University School of Medicine
Giorgio Palu, University of Padova
Catherine MT Sherwin, University of Utah

Catherine Sherwin, Section Editor

Dr. Catherine Sherwin is currently an Associate Professor

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