BMC Pharmacology and Toxicology

Featured article: Preventing angiogenesis inhibits oral cancer growth

Angiogenesis, the formation of new blood vessels from preexisting vessels, is critical for oral cancer development. Semaforin-3 (Sema3) is a secreted protein that prevents angiogenesis. Overexpression of Sema3 in oral tumor cell lines decreases tumor vasculature in vitro and decreases the size and capillary density of tumors in xenograft models of oral cancer in mice.

Flickr by Mike Seyfang

Metals have many essential functions in the brain and a large body of evidence supports important roles for altered metal stasis in many brain disorders. This article collection guest edited by Section Editor, Dr Michael Aschner provides a node for other researchers across diverse fields to access brain metal research and integrate this into their own programs.

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Aims and scope

BMC Pharmacology and Toxicology is an open access, peer-reviewed journal that considers articles on all aspects of chemically defined therapeutic and toxic agents. The journal welcomes submissions from all fields of experimental and clinical pharmacology including clinical trials.It is journal policy to publish work deemed by peer reviewers to be a coherent and sound addition to scientific knowledge and to put less emphasis on interest levels, provided that the research constitutes a useful contribution to the field.

Editor

Benjamin Ragen, BioMed Central

Section Editors

Michael Aschner, Albert Einstein College of Medicine
Phil Biggin, University of Oxford
Lucio Guido Costa, University of Washington
David H Farb, Boston University School of Medicine
Giorgio Palu, University of Padova
Catherine MT Sherwin, University of Utah

Catherine Sherwin, Section Editor

Dr. Catherine Sherwin is currently an Associate Professor

Meet our Section Editors

Data support service

Authors submitting to this journal can opt to use a new service that will make it easier to share research data.

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