BMC Pharmacology and Toxicology

Featured article: Tolerance to NSAIDS and opioids in the brain

Chronic NSAID administration in the anterior cingulate cortex can produce analgesic effects and chronic administration can result in tolerance. The authors also find that the effects of NSAIDs in the brain are mediated by the opioid system.

Content type: Research article
| 14 January 2019

Efficacy of the combination use of aprepitant and palonosetron for improving nausea in various moderately emetogenic chemotherapy regimens

Authors: Naohisa Yoshida, Tetsuya Taguchi, Masayoshi Nakanishi, Ken Inoue, Tetsuya Okayama, Takeshi Ishikawa, Eigo Otsuji, Koichi Takayama, Haruo Kuroboshi, Motohiro Kanazawa and Yoshito Itoh
Content type: Research article
| 14 January 2019

Adverse drug reactions associated with six commonly used antiepileptic drugs in southern China from 2003 to 2015

Authors: Yanru Du, Jiahe Lin, Jingzan Shen, Siqi Ding, Mengqian Ye, Li Wang, Yi Wang, Xinshi Wang, Niange Xia, Rongyuan Zheng, Hong Chen and Huiqin Xu
Content type: Research article
| 11 January 2019

Superior silybin bioavailability of silybin–phosphatidylcholine complex in oily-medium soft-gel capsules versus conventional silymarin tablets in healthy volunteers*

Authors: Méndez-Sánchez Nahum, Dibildox-Martinez Miguel, Sosa-Noguera Jahir, Sánchez-Medal Ramón and J.Francisco Flores-Murrieta
Content type: Research article
| 9 January 2019

In vitro wound healing of tumor cells: inhibition of cell migration by selected cytotoxic alkaloids

Authors: Xiaojuan Wang, Charlotte Caroline Decker, Laura Zechner, Sonja Krstin and Michael Wink
Content type: Technical advance
| 9 January 2019

Modified enzyme multiplied immunoassay technique of methotrexate assay to improve sensitivity and reduce cost

Authors: Xiaoping Shi, Hui Gao, Zhong Li, Jinghua Li, Yang Liu, Lujuan Li and Qi Zhang

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Content type: Review
| 5 January 2013

A review of the differences and similarities between generic drugs and their originator counterparts, including economic benefits associated with usage of generic medicines, using Ireland as a case study

Authors: Suzanne Dunne, Bill Shannon, Colum Dunne and Walter Cullen
Content type: Case report
| 4 May 2013

Rifampicin-warfarin interaction leading to macroscopic hematuria: a case report and review of the literature

Authors: Maria AP Martins, Adriano MM Reis, Mariana F Sales, Vandack Nobre, Daniel D Ribeiro, Manoel OC Rocha and Antônio LP Ribeiro
Content type: Research article
| 4 October 2013

Physiological and pharmacokinetic effects of oral 1,3-dimethylamylamine administration in men

Authors: Brian K Schilling, Kelley G Hammond, Richard J Bloomer, Chaela S Presley and Charles R Yates
Content type: Research article
| 23 April 2013

Pharmaceutical quality of seven generic Levodopa/Benserazide products compared with original Madopar® / Prolopa®

Authors: Urs E Gasser, Anton Fischer, Jan P Timmermans and Isabelle Arnet
Content type: Commentary
| 16 August 2014

An inevitable wave of prescription drug monitoring programs in the context of prescription opioids: pros, cons and tensions

Authors: M Mofizul Islam and Ian S McRae

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Aims and scope

BMC Pharmacology and Toxicology is an open access, peer-reviewed journal that considers articles on all aspects of chemically defined therapeutic and toxic agents. The journal welcomes submissions from all fields of experimental and clinical pharmacology including clinical trials.It is journal policy to publish work deemed by peer reviewers to be a coherent and sound addition to scientific knowledge and to put less emphasis on interest levels, provided that the research constitutes a useful contribution to the field.

Editor

Benjamin Ragen, BioMed Central

Section Editors

Michael Aschner, Albert Einstein College of Medicine
Phil Biggin, University of Oxford
Lucio Guido Costa, University of Washington
David H Farb, Boston University School of Medicine
Giorgio Palu, University of Padova
Catherine MT Sherwin, University of Utah

Catherine Sherwin, Section Editor

Dr. Catherine Sherwin is currently an Associate Professor

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