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Table 2 Descriptive parameters of the kinetics of serum Neopterin and serum β2-microglobulin increments (N = 12)

From: Pharmacokinetic and pharmacodynamic characterization of a new formulation containing synergistic proportions of interferons alpha-2b and gamma (HeberPAG®) in patients with mycosis fungoides: an open-label trial

Parameter

Neopterin

β2-microglobulin

Rmax

8.0 ± 4.2 ng/mL

2.7 ± 1.4 μg/mL

T(Rmax)

48 ± 24 h

24 ± 24 h

λ effect

0.02 ± 0.01 h-1

0.02 ± 0.01 h-1

t1/2 effect

40.3 ± 12.9 h

37.6 ± 15.9 h

AUEC

661 ± 322 ng.h/mL

195 ± 117 μg.h/mL

MET

80.6 ± 17.4 h

74.8 ± 21.9 h

  1. Data are reported as mean ± standard deviation, except for T(Rmax) expressed as median ± quartile range.