Table 2 Description of information collected for all ionic currents

channel type

For the cell lines heterologously expressing channel subunits: name of the gene encoding expressed subunits or name of expressed channel and its origin (r-rat; h-human)

in vitro cell model

Cell line used for channel subunits expression or cardiomyocytes origin (e.g. HEK, XO, guinea pig VM)

stimulation frequency [Hz]

Number of current provoking pulses delivered every second expressed in Hz

transfection type

Mode of channel expression in heterologous system (stable or transient)

temperature [⁰C]

Temperature maintained during experiment

technique

Technique used for current recordings

Ca2+ bath [mM]

Calcium ion concentration in the bath solution

K+ bath [mM]

Potassium ion concentration in the bath solution

Na+ bath [mM]

Sodium ion concentration in the bath solution

t1 pulse [ms]

Duration of first pulse in the step-protocol

t2 pulse [ms]

Duration of second pulse in the step-protocol

holding potential [mV]

The starting membrane voltage level

depolarization potential [mV]

Voltage of membrane depolarizing impulse

repolarization potential [mV]

Voltage of membrane repolarizing impulse

measurement potential [mV]

Membrane voltage level during current amplitude measurement

protocol

Type of voltage protocol applied to elicit current (e.g. step, AP, ramp)

data source

First author name and publication year

PMID

PubMed Unique Identifier, a unique number assigned to each PubMed record

IC50 [μM]

The concentration of compound that results in 50% inhibition of current in micromolar

comments

Additional information e.g. alternative naming, denotation of smiles and/or IUPAC name source if not PubChem; source of uncertainty