Table 3 Multivariable analysis of independent risk factors for nephrotoxicity
Variable | Odds ratio | 95% confidence interval |
|---|---|---|
Guideline-Recommended Vancomycin Dosing | 1.52 | 0.75-3.08 |
Vancomycin duration greater than 15 days | 3.36 | 1.79-6.34 |
Weight greater than 100 kilograms | 2.74 | 1.27-5.91 |
Pitt Bacteremia Score of four or greater | 2.73 | 1.29-5.79 |
Vancomycin trough greater than 20 mcg/ml | 2.36 | 1.07-5.20 |
Age greater than 52 years | 2.10 | 1.08-4.08 |
Intensive care unit residence | 1.90 | 0.95-3.80 |
Concomitant nephrotoxin | 1.64 | 0.87-3.11 |