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Figure 9 | BMC Pharmacology and Toxicology

Figure 9

From: Label-free integrative pharmacology on-target of opioid ligands at the opioid receptor family

Figure 9

Dose responses of a panel of opioid ligands in HEK-KOR cells. (a) Dose dependent responses of opioid ligands obtained using DMR agonist assays. The maximal amplitudes were plotted as a function of agonist doses. Data represents the mean ± s.d. for 2 independent measurements, each in duplicate (n = 4). (b) Dose-dependent inhibition of the DMR of 64 nM BRL-57532 by opioid ligands. The maximal amplitudes of the BRL-57532 DMR were plotted as a function of ligand doses. Data represents the mean ± s.d. for 2 independent measurements, each in duplicate (n = 4).

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