Table 1 Fatal consumer cases reported for nervous systems medications in Europe, 2007 to 2011
From: Adverse drug reactions reported by consumers for nervous system medications in Europe 2007 to 2011
Case no. | Medicine (s) | ATC group | Adverse drug reaction (s) | Sex (M/F) | Age |
|---|---|---|---|---|---|
1 | Diamorphine | N02AA09 | Sudden death | F | 18+ |
2 | Metamizole | N02BB02 | Agranulocytosis | F | 18+ |
Leukopenia | |||||
Multi-organ failure | |||||
Sepsis/septic shock | |||||
3 | Morphine | N02AA01 | Cerebrovascular accident | F | 18+ |
4 | Oxycodone | N02AA05 | Intentional overdose/suicidal ideation | M | 18+ |
5 | Apomorphine | N04BC07 | Pneumonia | M | NA |
6 | Apomorphine | N04BC07 | Intestinal haemorrhage | M | NA |
Pneumonia aspiration | |||||
7 | Apomorphine | N04BC07 | Anaemia | F | 18+ |
Haematocrit decreased | |||||
Red blood cell sedimentation rate increased | |||||
8 | Apomorphine | N04BC07 | Death | F | NA |
9 | Apomorphine | N04BC07 | Death | F | 18+ |
10 | Apomorphine | N04BC07 | Death | F | NA |
11 | Apomorphine | N04BC07 | Death | F | 18+ |
12 | Carbidopa/levodopa | N04BA02 | Death | M | 18+ |
Entacapone, Rotigotine | |||||
13 | Clomethiazole | N05CM02 | Leucocytosis | F | NA |
Pyrexia | |||||
Musculoskeletal stiffness | |||||
Neuroleptic malignant syndrome | |||||
14 | Clozapine | N05AH02 | Cardiac failure | F | 18+ |
Somnolence | |||||
15 | Citalopram | N06AB04 | Fatigue/malaise | F | NA |
16 | Duloxetine | N06AX21 | Deafness | F | 18+ |
Abasia | |||||
Urinary tract infection | |||||
Septic shock | |||||
Urosepsis | |||||
Hyponatraemia | |||||
Neoplasm malignant | |||||
Aphasia | |||||
Urinary incontinence | |||||
Renal failure | |||||
17 | Trimipramine | N06AA06 | Asthenia | M | 18+ |
Depressed level of consciousness/sedation | |||||
Tachyphrenia | |||||
Completed suicide | |||||
Dependence | |||||
Indifference | |||||
18 | Amitriptyline | N06AA09 | Toxicity to various agents | M | NA |
19 | Rivastigmine | N06DA03 | Lung infection | F | 18+ |
Mood altered/aggression |