Computational analysis of protein-protein interfaces involving an alpha helix: insights for terphenyl–like molecules binding

Table 3 Geometrical and physicochemical characteristics of the identified pockets

Protein code PDB	Volume (Å³)	Hydrophobicity score	Local hydrophobic density
Chicken calmodulin	312.0	68.86	43.00
2O5G	312.0	68.86	43.00
Human calmodulin	203.0	68.86	42.00
1ZUZ	203.0	68.86	42.00
Human calmodulin	219.8	59.62	40.00
2VAY	219.8	59.62	40.00
Human calmodulin	226.4	61.00	39.32
3DVE	226.4	61.00	39.32
E.coli calmodulin	317.9	56.63	40.15
1QTX	317.9	56.63	40.15
Rat calmodulin	310.6	56.62	43.78
2HQW	310.6	56.62	43.78
Human centrin 2	147.9	41.47	32.00
2GGM	147.9	41.47	32.00
Human centrin 2	210.9	39.93	35.08
2K2I	210.9	39.93	35.08
Scherffelia dubia centrin	221.5	58.19	31.00
3KF9	221.5	58.19	31.00
Human BCL-XL	321.5	36.91	42.04
1BXL	321.5	36.91	42.04
Human E3 ubiquitin-protein ligase MDM2	201.9	51.18	55.20
1YCR			55.20
Rabbit cardiac troponin C	213.1	63.07	39.15
1A2X

ISSN: 2050-6511